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4EKX

Crystal Structure of YLDV 14L IL-18 Binding Protein in Complex with Human IL-18

Summary for 4EKX
Entry DOI10.2210/pdb4ekx/pdb
Related4EEE
Descriptor14L protein, Interleukin-18 (3 entities in total)
Functional Keywordsbinding protein, beta trefoil, immunoglobulin fold, yldv, yaba, yatapoxvirus, 14l, cytokine signaling, cytokine-viral protein complex, cytokine/viral protein
Biological sourceYaba-like disease virus (YLDV)
More
Cellular locationSecreted: Q14116
Total number of polymer chains4
Total formula weight63384.26
Authors
Krumm, B.E.,Xiang, Y.,Deng, J. (deposition date: 2012-04-10, release date: 2012-09-26, Last modification date: 2017-11-15)
Primary citationKrumm, B.,Meng, X.,Wang, Z.,Xiang, Y.,Deng, J.
A unique bivalent binding and inhibition mechanism by the yatapoxvirus interleukin 18 binding protein.
Plos Pathog., 8:e1002876-e1002876, 2012
Cited by
PubMed: 22927815
DOI: 10.1371/journal.ppat.1002876
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

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