4HJJ
Structure Reveals Function of the Dual Variable Domain Immunoglobulin (DVD-Ig) Molecule
Summary for 4HJJ
Entry DOI | 10.2210/pdb4hjj/pdb |
Related | 2VXV |
Descriptor | Interleukin-18, Anti-IL12 Anti-IL18 DFab Heavy Chain, Anti-IL12 Anti-IL18 DFab Light Chain, ... (7 entities in total) |
Functional Keywords | dfab complex, il-18, dual variable domain immunoglobulin, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: Q14116 |
Total number of polymer chains | 3 |
Total formula weight | 91905.16 |
Authors | Jakob, C.G.,Edalji, R.,Judge, R.A.,DiGiammarino, E.,Li, Y.,Gu, J.,Ghayur, T. (deposition date: 2012-10-12, release date: 2013-05-08) |
Primary citation | Jakob, C.G.,Edalji, R.,Judge, R.A.,Digiammarino, E.,Li, Y.,Gu, J.,Ghayur, T. Structure reveals function of the dual variable domain immunoglobulin (DVD-Ig[TM]) molecule MAbs, 5:358-363, 2013 Cited by PubMed: 23549062DOI: 10.4161/mabs.23977 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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