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2QBV
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Crystal Structure of Intracellular Chorismate Mutase from Mycobacterium Tuberculosis
分子名称: CHORISMATE MUTASE
著者Ladner, J.E, Reddy, P.T, Kim, S.K, Reddy, S.-K, Nelson, B.C.
登録日2007-06-18
公開日2007-06-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A comparative biochemical and structural analysis of the intracellular chorismate mutase (Rv0948c) from Mycobacterium tuberculosis H(37)R(v) and the secreted chorismate mutase (y2828) from Yersinia pestis.
Febs J., 275, 2008
2QBW
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BU of 2qbw by Molmil
The crystal structure of PDZ-Fibronectin fusion protein
分子名称: PDZ-Fibronectin fusion protein, Polypeptide
著者Huang, J, Makabe, K, Koide, A, Koide, S.
登録日2007-06-18
公開日2008-04-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design of protein function leaps by directed domain interface evolution.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2QBX
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BU of 2qbx by Molmil
EphB2/SNEW Antagonistic Peptide Complex
分子名称: Ephrin type-B receptor 2, SULFATE ION, antagonistic peptide
著者Chrencik, J.E, Brooun, A, Recht, M.I, Nicola, G, Pasquale, E.B, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
登録日2007-06-18
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition.
J.Biol.Chem., 282, 2007
2QBY
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BU of 2qby by Molmil
Crystal structure of a heterodimer of Cdc6/Orc1 initiators bound to origin DNA (from S. solfataricus)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 6 homolog 1, Cell division control protein 6 homolog 3, ...
著者Cunningham Dueber, E.L, Corn, J.E, Bell, S.D, Berger, J.M.
登録日2007-06-18
公開日2007-09-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Replication origin recognition and deformation by a heterodimeric archaeal Orc1 complex.
Science, 317, 2007
2QBZ
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BU of 2qbz by Molmil
Structure of the M-Box Riboswitch Aptamer Domain
分子名称: M-Box RNA, ykoK riboswitch aptamer, MAGNESIUM ION, ...
著者Dann III, C.E, Winkler, W.C.
登録日2007-06-18
公開日2007-09-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and mechanism of a metal-sensing regulatory RNA
Cell(Cambridge,Mass.), 130, 2007
2QC1
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BU of 2qc1 by Molmil
Crystal structure of the extracellular domain of the nicotinic acetylcholine receptor 1 subunit bound to alpha-bungarotoxin at 1.9 A resolution
分子名称: Acetylcholine receptor subunit alpha, Alpha-bungarotoxin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Dellisanti, C.D, Yao, Y, Stroud, J.C, Wang, Z, Chen, L.
登録日2007-06-18
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution.
Nat.Neurosci., 10, 2007
2QC2
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Crystal structure of Severe Acute Respiratory Syndrome (SARS) 3C-like protease Asn214Ala mutant
分子名称: 3C-like proteinase
著者Shi, J.H.
登録日2007-06-19
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of Severe Acute Respiratory Syndrome (SARS) 3C-like protease Asn214Ala mutant with two non-native n-terminal residues (GLY AND SER)
To be Published
2QC3
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Crystal structure of MCAT from Mycobacterium tuberculosis
分子名称: ACETIC ACID, Malonyl CoA-acyl carrier protein transacylase
著者Li, Z, Huang, Y, Ge, J, Bartlam, M, Wang, H, Rao, Z.
登録日2007-06-19
公開日2007-08-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of MCAT from Mycobacterium tuberculosis Reveals Three New Catalytic Models.
J.Mol.Biol., 371, 2007
2QC5
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Streptogramin B lyase structure
分子名称: IODIDE ION, Streptogramin B lactonase
著者Lipka, M, Bochtler, M.
登録日2007-06-19
公開日2008-10-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure and mechanism of the Staphylococcus cohnii virginiamycin B lyase (Vgb).
Biochemistry, 47, 2008
2QC6
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Protein kinase CK2 in complex with DBC
分子名称: 3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE, Casein kinase II subunit alpha
著者Battistutta, R.
登録日2007-06-19
公開日2008-02-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships.
J.Med.Chem., 51, 2008
2QC7
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Crystal structure of the protein-disulfide isomerase related chaperone ERp29
分子名称: Endoplasmic reticulum protein ERp29
著者Barak, N.N, Sevvana, M, Neumann, P, Malesevic, M, Naumann, K, Fischer, G, Sheldrick, G.M, Stubbs, M.T, Ferrari, D.M.
登録日2007-06-19
公開日2008-06-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure and functional analysis of the protein disulfide isomerase-related protein ERp29.
J.Mol.Biol., 385, 2009
2QC8
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BU of 2qc8 by Molmil
Crystal structure of human glutamine synthetase in complex with ADP and methionine sulfoximine phosphate
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Glutamine synthetase, ...
著者Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hogbom, M, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日2007-06-19
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design.
J.Mol.Biol., 375, 2008
2QC9
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Mouse Notch 1 Ankyrin Repeat Intracellular Domain
分子名称: Notch 1 protein
著者McDonough, M.A, Schofield, C.J.
登録日2007-06-19
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor.
J.Biol.Chem., 282, 2007
2QCA
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BU of 2qca by Molmil
A New Crystal Form of Bovine Pancreatic RNase A in Complex with 2'-Deoxyguanosine-5'-monophosphate
分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, Ribonuclease pancreatic
著者Larson, S.B, Day, J.S, Cudney, R, McPherson, A, Center for High-Throughput Structural Biology (CHTSB)
登録日2007-06-19
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献A new crystal form of bovine pancreatic RNase A in complex with 2'-deoxyguanosine-5'-monophosphate.
Acta Crystallogr.,Sect.F, 63, 2007
2QCB
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BU of 2qcb by Molmil
T7-tagged full-length streptavidin complexed with ruthenium ligand
分子名称: N-(4-{[(2-AMINOETHYL)AMINO]SULFONYL}PHENYL)-5-[(3AS,4S,6AR)-2-OXOHEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL]PENTANAMIDE-(1,2,3,4,5,6-ETA)-BENZENE-CHLORO-RUTHENIUM(III), Streptavidin
著者Le Trong, I, Creus, M, Pordea, A, Ward, T.R, Stenkamp, R.E.
登録日2007-06-19
公開日2008-04-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献X-ray structure and designed evolution of an artificial transfer hydrogenase
Angew.Chem.Int.Ed.Engl., 47, 2008
2QCC
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BU of 2qcc by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase, apo form
分子名称: GLYCEROL, Orotidine 5'- phosphate decarboxylase (OMPdecase), SULFATE ION
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCD
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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to UMP
分子名称: URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCE
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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to sulfate, glycerol, and chloride
分子名称: CHLORIDE ION, GLYCEROL, SULFATE ION, ...
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCF
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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP
分子名称: 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, GLYCEROL, Uridine 5'-monophosphate synthase (UMP synthase)
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCG
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BU of 2qcg by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-bromo-UMP
分子名称: 5-BROMO-URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCH
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BU of 2qch by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-iodo-UMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-IODO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, IODIDE ION, ...
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCI
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HIV-1 Protease mutant D30N with potent Antiviral inhibitor GRL-98065
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(2S,3R)-3-HYDROXY-4-(N-ISOBUTYLBENZO[D][1,3]DIOXOLE-5-SULFONAMIDO)-1-PHENYLBUTAN-2-YLCARBAMATE, ACETATE ION, CHLORIDE ION, ...
著者Wang, Y.F, Tie, Y, Boross, P.I, Tozser, J, Ghosh, A.K, Harrison, R.W, Weber, I.T.
登録日2007-06-19
公開日2008-04-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Potent new antiviral compound shows similar inhibition and structural interactions with drug resistant mutants and wild type HIV-1 protease.
J.Med.Chem., 50, 2007
2QCJ
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Native Structure of Lyp
分子名称: Tyrosine-protein phosphatase non-receptor type 22
著者Sun, J.P, Yu, X, Zhang, Z.Y.
登録日2007-06-19
公開日2007-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of Lyp and its complex with a selective inhibitor
To be Published
2QCK
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Crystal structure of flavin reductase domain protein (YP_831077.1) from Arthrobacter sp. FB24 at 1.90 A resolution
分子名称: Flavin reductase domain protein, PHOSPHATE ION
著者Joint Center for Structural Genomics (JCSG)
登録日2007-06-19
公開日2007-07-03
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of flavin reductase domain protein (YP_831077.1) from Arthrobacter sp. FB24 at 1.90 A resolution
To be published
2QCL
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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to OMP
分子名称: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
著者Wittmann, J, Rudolph, M.
登録日2007-06-19
公開日2007-11-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008

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