2QC6

Protein kinase CK2 in complex with DBC

Summary for 2QC6

Entry DOI	10.2210/pdb2qc6/pdb
Descriptor	Casein kinase II subunit alpha, 3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE (3 entities in total)
Functional Keywords	ck2, dbc, kinase inhibitors, coumarins, transferase
Biological source	Zea mays
Total number of polymer chains	1
Total formula weight	39641.13
Authors	Battistutta, R. (deposition date: 2007-06-19, release date: 2008-02-26, Last modification date: 2011-07-13)
Primary citation	Chilin, A.,Battistutta, R.,Bortolato, A.,Cozza, G.,Zanatta, S.,Poletto, G.,Mazzorana, M.,Zagotto, G.,Uriarte, E.,Guiotto, A.,Pinna, L.A.,Meggio, F.,Moro, S. Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships. J.Med.Chem., 51:752-759, 2008 Cited by PubMed: 18251491 DOI: 10.1021/jm070909t PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation