2QC1
Crystal structure of the extracellular domain of the nicotinic acetylcholine receptor 1 subunit bound to alpha-bungarotoxin at 1.9 A resolution
Summary for 2QC1
Entry DOI | 10.2210/pdb2qc1/pdb |
Descriptor | Alpha-bungarotoxin, Acetylcholine receptor subunit alpha, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | nicotinic acetylcholine receptor, glycosylated protein, beta sandwich, cys-loop, buried hydrophilic residues, protein binding |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 34483.87 |
Authors | Dellisanti, C.D.,Yao, Y.,Stroud, J.C.,Wang, Z.,Chen, L. (deposition date: 2007-06-18, release date: 2007-08-07, Last modification date: 2023-08-30) |
Primary citation | Dellisanti, C.D.,Yao, Y.,Stroud, J.C.,Wang, Z.Z.,Chen, L. Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution. Nat.Neurosci., 10:953-962, 2007 Cited by PubMed: 17643119DOI: 10.1038/nn1942 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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