2QCC
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase, apo form
Summary for 2QCC
Entry DOI | 10.2210/pdb2qcc/pdb |
Related | 2jgy 2v30 |
Descriptor | Orotidine 5'- phosphate decarboxylase (OMPdecase), SULFATE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | ump synthase, decarboxylase, tim barrel, catalytic proficiency, lyase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 56975.80 |
Authors | Wittmann, J.,Rudolph, M. (deposition date: 2007-06-19, release date: 2007-11-06, Last modification date: 2024-02-21) |
Primary citation | Wittmann, J.G.,Heinrich, D.,Gasow, K.,Frey, A.,Diederichsen, U.,Rudolph, M.G. Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16:82-92, 2008 Cited by PubMed: 18184586DOI: 10.1016/j.str.2007.10.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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