2QCC

Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase, apo form

Summary for 2QCC

Entry DOI	10.2210/pdb2qcc/pdb
Related	2jgy 2v30
Descriptor	Orotidine 5'- phosphate decarboxylase (OMPdecase), SULFATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	ump synthase, decarboxylase, tim barrel, catalytic proficiency, lyase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	56975.80
Authors	Wittmann, J.,Rudolph, M. (deposition date: 2007-06-19, release date: 2007-11-06, Last modification date: 2024-02-21)
Primary citation	Wittmann, J.G.,Heinrich, D.,Gasow, K.,Frey, A.,Diederichsen, U.,Rudolph, M.G. Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16:82-92, 2008 Cited by PubMed: 18184586 DOI: 10.1016/j.str.2007.10.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation