PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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6DOY	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM Li+ for 120 s at 21 C 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
7LV3	Crystal structure of human protein kinase G (PKG) R-C complex in inhibited state 分子名称: 1,2-ETHANEDIOL, Isoform Beta of cGMP-dependent protein kinase 1, MANGANESE (II) ION, ... 著者 Sharma, R, Lying, Q, Casteel, D, Kim, C. 登録日 2021-02-23 公開日 2022-08-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 An auto-inhibited state of protein kinase G and implications for selective activation. Elife, 11, 2022
2GFW	Structure of wild type E. coli FabF (KASII) 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2 著者 Soisson, S.M, Parthasarathy, G. 登録日 2006-03-23 公開日 2006-05-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature, 441, 2006
2GG7	Novel bacterial methionine aminopeptidase inhibitors 分子名称: 3-(5-AMINO-3-IMINO-3H-PYRAZOL-4-YLAZO)-BENZOIC ACID, COBALT (II) ION, Methionine aminopeptidase, ... 著者 Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M. 登録日 2006-03-23 公開日 2006-06-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors. Proteins, 66, 2007
1MSS	LARGE SCALE STRUCTURAL REARRANGEMENTS OF THE FRONT LOOPS IN MONOMERISED TRIOSEPHOSPHATE ISOMERASE, AS DEDUCED FROM THE COMPARISON OF THE STRUCTURAL PROPERTIES OF MONOTIM AND ITS POINT MUTATION VARIANT MONOSS 分子名称: TRIOSEPHOSPHATE ISOMERASE 著者 Radha Kishan, K.V, Wierenga, R.K. 登録日 1994-07-27 公開日 1994-09-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Three new crystal structures of point mutation variants of monoTIM: conformational flexibility of loop-1, loop-4 and loop-8. Structure, 3, 1995
2FY5	Structures of ligand bound human choline acetyltransferase provide insight into regulation of acetylcholine synthesis 分子名称: Choline O-acetyltransferase, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-3-HYDROXY-2,2-DIMETHYL-4-OXO-4-{[3-OXO-3-({2-[(2-OXOPROPYL)THIO]ETHYL}AMINO)PROPYL]AMINO}BUTYL DIHYDROGEN DIPHOSPHATE 著者 Kim, A.R, Rylett, R.J, Shilton, B.H. 登録日 2006-02-07 公開日 2006-12-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Substrate binding and catalytic mechanism of human choline acetyltransferase. Biochemistry, 45, 2006
1MXX	crystal titration experiments (AMPA co-crystals soaked in 100 uM BrW) 分子名称: GLUTAMATE RECEPTOR 2, ZINC ION 著者 Jin, R, Gouaux, E. 登録日 2002-10-03 公開日 2003-06-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
7ROV	KRAS G12D Mutant in complex with GMPPCP and cyclic peptide MP-9903 分子名称: Cyclic peptide MP-9903, GLYCEROL, Isoform 2B of GTPase KRas, ... 著者 Orth, P. 登録日 2021-08-02 公開日 2021-09-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling. Chem Sci, 12, 2021
1MX8	Two homologous rat cellular retinol-binding proteins differ in local structure and flexibility 分子名称: CELLULAR RETINOL-BINDING PROTEIN I, HOLO, RETINOL 著者 Lu, J, Cistola, D.P, Li, E. 登録日 2002-10-01 公開日 2003-07-29 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Two homologous rat cellular retinol-binding proteins differ in local conformational flexibility. J.Mol.Biol., 330, 2003
2G2U	Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) complex 分子名称: Beta-lactamase SHV-1, Beta-lactamase inhibitory protein 著者 Reynolds, K.A, Thomson, J.M, Corbett, K.D, Bethel, C.R, Berger, J.M, Kirsch, J.F, Bonomo, R.A, Handel, T.M. 登録日 2006-02-16 公開日 2006-07-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface. J.Biol.Chem., 281, 2006
1N20	(+)-Bornyl Diphosphate Synthase: Complex with Mg and 3-aza-2,3-dihydrogeranyl diphosphate 分子名称: (+)-bornyl diphosphate synthase, 2-[METHYL-(4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, MAGNESIUM ION 著者 Whittington, D.A, Wise, M.L, Urbansky, M, Coates, R.M, Croteau, R.B, Christianson, D.W. 登録日 2002-10-21 公開日 2002-11-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Bornyl Diphosphate Synthase: Structure and Strategy for Carbocation Manipulation by a Terpenoid Cyclase Proc.Natl.Acad.Sci.USA, 99, 2002
6DK3	HUMAN MITOCHONDRIAL SERINE HYDROXYMETHYLTRANSFERASe 2 分子名称: Serine hydroxymethyltransferase, mitochondrial, UNKNOWN ATOM OR ION 著者 Dong, A, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) 登録日 2018-05-28 公開日 2018-06-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 HUMAN MITOCHONDRIAL SERINE HYDROXYMETHYLTRANSFERASe 2 to be published
2GDN	Crystal structure of the Mycobacterium tuberculosis beta-lactamase 分子名称: Beta-lactamase 著者 Wang, F, Cassidy, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2006-03-16 公開日 2006-04-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Crystal Structure and Activity Studies of the Mycobacterium tuberculosis {beta}-Lactamase Reveal Its Critical Role in Resistance to {beta}-Lactam Antibiotics. Antimicrob.Agents Chemother., 50, 2006
2G78	Crystal Structure of the R132K:Y134F Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans-Retinoic Acid at 1.70 Angstroms Resolution 分子名称: Cellular retinoic acid-binding protein 2, RETINOIC ACID, SODIUM ION 著者 Vaezeslami, S, Geiger, J.H. 登録日 2006-02-27 公開日 2007-04-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Protein design: reengineering cellular retinoic acid binding protein II into a rhodopsin protein mimic. J.Am.Chem.Soc., 129, 2007
7LVA	Solution structure of the HIV-1 PBS-segment 分子名称: RNA (103-MER) 著者 Heng, X, Song, Z. 登録日 2021-02-24 公開日 2021-03-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR, SOLUTION SCATTERING 主引用文献 The three-way junction structure of the HIV-1 PBS-segment binds host enzyme important for viral infectivity. Nucleic Acids Res., 49, 2021
2GFY	Structure of E. coli FabF(K335A) mutant with covalently linked dodecanoic acid 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, LAURIC ACID 著者 Soisson, S.M, Parthasarathy, G. 登録日 2006-03-23 公開日 2006-05-23 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature, 441, 2006
7RCO	Crystal structure of human TGF-beta-2 bound to 4A11.V2 Fab 分子名称: 4A11.V2 Fab Heavy Chain, 4A11.V2 Fab Light Chain, Transforming growth factor beta-2 著者 Yin, J, Lupardus, P.J, Sudhamsu, J. 登録日 2021-07-07 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Dramatic activation of an antibody by a single amino acid change in framework. Sci Rep, 11, 2021
6DOG	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 600 s at 21 C 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.285 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DOU	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 5 mM Mg2+ and 200 mM Rb+ for 120 s at 21 C 分子名称: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.487 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
1MWN	Solution NMR structure of S100B bound to the high-affinity target peptide TRTK-12 分子名称: CALCIUM ION, F-actin capping protein alpha-1 subunit, S-100 protein, ... 著者 Inman, K.G, Yang, R, Rustandi, R.R, Miller, K.E, Baldisseri, D.M, Weber, D.J. 登録日 2002-09-30 公開日 2002-12-18 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution NMR structure of S100B bound to the high-affinity target peptide TRTK-12 J.Mol.Biol., 324, 2002
6DPN	Crystal Structure of Bacillus Halodurans Ribonuclease H1 E188A in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 200 s at 21 C 分子名称: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), 5'-R(P*CP*G)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.493 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
7R8W	Crystal Structure of the LNK SH2 Domain in Complex with a JAK2 pY813 Phosphopeptide 分子名称: JAK2 pY813 phosphopeptide, SH2B adapter protein 3 著者 Morris, R, Kershaw, N.J, Babon, J.J. 登録日 2021-06-27 公開日 2021-10-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional analysis of target recognition by the lymphocyte adaptor protein LNK. Nat Commun, 12, 2021
2GA0	Variable Small Protein 1 of Borrelia turicatae (VspA or Vsp1) 分子名称: NICKEL (II) ION, surface protein VspA 著者 Lawson, C.L, Yung, B.H, Barbour, A.G, Zuckert, W.R. 登録日 2006-03-07 公開日 2006-06-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of neurotropism-associated variable surface protein 1 (Vsp1) of Borrelia turicatae. J.Bacteriol., 188, 2006
2GB4	Crystal structure of Thiopurine methyltransferase (18204406) from Mus musculus at 1.35 A resolution 分子名称: S-ADENOSYL-L-HOMOCYSTEINE, Thiopurine S-methyltransferase 著者 Joint Center for Structural Genomics (JCSG) 登録日 2006-03-09 公開日 2006-09-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Crystal structure of Thiopurine methyltransferase (18204406) from Mus musculus at 1.35 A resolution To be published
1N22	(+)-Bornyl Diphosphate Synthase: Complex with Mg, pyrophosphate, and (4R)-7-aza-7,8-dihydrolimonene 分子名称: (+)-bornyl diphosphate synthase, (1R)-DIMETHYL-(4-METHYL-CYCLOHEX-3-ENYL)-AMINE, MAGNESIUM ION, ... 著者 Whittington, D.A, Wise, M.L, Urbansky, M, Coates, R.M, Croteau, R.B, Christianson, D.W. 登録日 2002-10-21 公開日 2002-11-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Bornyl diphosphate synthase: Structure and strategy for carbocation manipulation by a terpenoid cyclase Proc.Natl.Acad.Sci.USA, 99, 2002

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