PDB: 41592 件ウェブページステータス検索Chemie searchBIRD

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2JXZ	Solution Conformation of A Non-Amyloidogenic Analogue of Human Calcitonin in Sodium Dodecyl Sulfate Micelles 分子名称: Calcitonin 著者 Andreotti, G, Vitale, R, Avidan-Shpalter, C, Amodeo, P, Gazit, E, Motta, A. 登録日 2007-12-03 公開日 2008-11-25 最終更新日 2011-07-13 実験手法 SOLUTION NMR 主引用文献 Converting the highly amyloidogenic human calcitonin into a powerful fibril inhibitor by 3D structure homology with a non-amyloidogenic analogue J.Biol.Chem., 286, 2011
4LY9	Human GKRP complexed to AMG-1694 [(2R)-1,1,1-trifluoro-2-{4-[(2S)-2-{[(3S)-3-methylmorpholin-4-yl]methyl}-4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol] and sorbitol-6-phosphate 分子名称: (2R)-1,1,1-trifluoro-2-{4-[(2S)-2-{[(3S)-3-methylmorpholin-4-yl]methyl}-4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... 著者 Jordan, S.R. 登録日 2013-07-30 公開日 2013-11-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors. Nature, 504, 2013
2GR2	Crystal structure of Ferredoxin reductase, BphA4 (oxidized form) 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, FLAVIN-ADENINE DINUCLEOTIDE, ferredoxin reductase 著者 Senda, T, Senda, M. 登録日 2006-04-22 公開日 2007-05-22 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A ferredoxin reductase BphA4 uses a butterfly motion of FAD to regulate affinity for ferredoxin To be Published
2JVI	NMR Solution Structure of the Hyper-Sporulation Response Regulator Spo0F Mutant H101A from Bacillus subtilis 分子名称: Sporulation initiation phosphotransferase F 著者 Bobay, B.G, McLaughlin, P.D, Thompson, R.J, Hoch, J.A, Cavanagh, J. 登録日 2007-09-20 公開日 2008-02-05 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Covariance identifies dynamic residues at the interfaces in protein/protein complexes To be Published
1POB	CRYSTAL STRUCTURE OF COBRA-VENOM PHOSPHOLIPASE A2 IN A COMPLEX WITH A TRANSITION-STATE ANALOGUE 分子名称: 1-O-OCTYL-2-HEPTYLPHOSPHONYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, CALCIUM ION, PHOSPHOLIPASE A2 著者 White, S.P, Scott, D.L, Otwinowski, Z, Sigler, P.B. 登録日 1992-09-07 公開日 1993-10-31 最終更新日 2019-08-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of cobra-venom phospholipase A2 in a complex with a transition-state analogue. Science, 250, 1990
2MKA	Spatial structure of the Toll-like receptor 3 transmembrane domain in the trimeric state 分子名称: Toll-like receptor 3 著者 Mineev, K, Gonscharuk, S.A, Arseniev, A.S. 登録日 2014-02-04 公開日 2014-09-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Toll-like receptor 3 transmembrane domain is able to perform various homotypic interactions: An NMR structural study. Febs Lett., 588, 2014
2MK9	Spatial structure of the dimeric transmembrane domain of Toll-like receptor 3 分子名称: Toll-like receptor 3 著者 Mineev, K.S, Goncharuk, S.A, Arseniev, A.S. 登録日 2014-02-04 公開日 2014-09-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Toll-like receptor 3 transmembrane domain is able to perform various homotypic interactions: An NMR structural study. Febs Lett., 588, 2014
2FGY	Beta Carbonic Anhydrase from the Carboxysomal Shell of Halothiobacillus neapolitanus (CsoSCA) 分子名称: ZINC ION, carboxysome shell polypeptide 著者 Sawaya, M.R. 登録日 2005-12-22 公開日 2006-01-17 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Structure of beta-carbonic anhydrase from the carboxysomal shell reveals a distinct subclass with one active site for the price of two. J.Biol.Chem., 281, 2006
2QP2	Structure of a MACPF/perforin-like protein 分子名称: CALCIUM ION, Unknown protein 著者 Rosado, C.J, Buckle, A.M, Law, R.H.P, Butcher, R.E, Kan, W.T, Bird, C.H, Ung, K, Browne, K.A, Baran, K, Bashtannyk-Puhalovich, T.A, Faux, N.G, Wong, W, Porter, C.J, Pike, R.N, Ellisdon, A.M, Pearce, M.C, Bottomley, S.P, Emsley, J, Smith, A.I, Rossjohn, J, Hartland, E.L, Voskoboinik, I, Trapani, J.A, Bird, P.I, Dunstone, M.A, Whisstock, J.C. 登録日 2007-07-22 公開日 2007-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A common fold mediates vertebrate defense and bacterial attack Science, 317, 2007
5T47	Crystal structure of the D. melanogaster eIF4E-eIF4G complex 分子名称: Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, isoform A, ... 著者 Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E. 登録日 2016-08-29 公開日 2016-10-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation. Mol.Cell, 64, 2016
5T46	Crystal structure of the human eIF4E-eIF4G complex 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E, ... 著者 Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E. 登録日 2016-08-29 公開日 2016-10-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation. Mol.Cell, 64, 2016
5T48	Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, ... 著者 Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E. 登録日 2016-08-29 公開日 2016-10-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation. Mol.Cell, 64, 2016
5SUY	Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from dimeric fraction 分子名称: SULFATE ION, Segment polarity protein dishevelled homolog DVL-2 著者 Renko, M, Gammons, M.V, Bienz, M. 登録日 2016-08-04 公開日 2016-10-12 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled. Mol.Cell, 64, 2016
5SUZ	Domain-swapped dimer of human Dishevelled2 DEP domain: C-centered monoclinic crystal form crystallised from monomeric fraction 分子名称: Segment polarity protein dishevelled homolog DVL-2 著者 Renko, M, Gammons, M.V, Bienz, M. 登録日 2016-08-04 公開日 2016-10-12 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled. Mol.Cell, 64, 2016
5THL	Crystal structure of the human tyrosyl-tRNA synthetase mutant G41R 分子名称: Tyrosine--tRNA ligase, cytoplasmic 著者 Blocquel, D, Sajish, M, Yang, X.L. 登録日 2016-09-29 公開日 2017-06-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy. Nucleic Acids Res., 45, 2017
5THH	Crystal structure of a human tyrosyl-tRNA synthetase mutant 分子名称: TYROSINE, Tyrosine--tRNA ligase, cytoplasmic 著者 Blocquel, D, Yang, X.L. 登録日 2016-09-29 公開日 2017-05-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.959 Å) 主引用文献 Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy. Nucleic Acids Res., 45, 2017
2W0T	Solution structure of the FCS zinc finger domain of human LMBL2 分子名称: LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE 2 PROTEIN, ZINC ION 著者 Lechtenberg, B.C, Allen, M.D, Bycroft, M. 登録日 2008-10-10 公開日 2009-01-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the Fcs Zinc Finger Domain of the Human Polycomb Group Protein L(3)Mbt-Like 2. Protein Sci., 18, 2009
2VUK	Structure of the p53 core domain mutant Y220C bound to the stabilizing small-molecule drug PhiKan083 分子名称: 1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine, CELLULAR TUMOR ANTIGEN P53, ZINC ION 著者 Joerger, A.C, Boeckler, F.M, Fersht, A.R. 登録日 2008-05-26 公開日 2008-07-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Targeted Rescue of a Destabilized Mutant of P53 by an in Silico Screened Drug. Proc.Natl.Acad.Sci.USA, 105, 2008
2X0W	STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 5,6-dimethoxy- 2-methylbenzothiazole 分子名称: 5,6-DIMETHOXY-2-METHYL-1,3-BENZOTHIAZOLE, CELLULAR TUMOR ANTIGEN P53, ZINC ION 著者 Kaar, J.L, Basse, N, Joerger, A.C, Fersht, A.R. 登録日 2009-12-17 公開日 2010-01-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant. Chem.Biol., 17, 2010
8ERF	HTLV-1 capsid protein N-terminal domain orthorhombic crystal form 分子名称: SULFATE ION, capsid protein p24 著者 Yu, R.J, Li, N, Jacques, D.A. 登録日 2022-10-11 公開日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 HTLV-1 capsid protein N-terminal domain orthorhombic crystal form To Be Published
3ERF	Crystal structure of Gtt2 from Saccharomyces cerevisiae 分子名称: Glutathione S-transferase 2 著者 Ma, X.X, Jiang, Y.L, He, Y.X, Chen, Y.X, Zhou, C.Z. 登録日 2008-10-02 公開日 2009-10-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Structures of yeast glutathione-S-transferase Gtt2 reveal a new catalytic type of GST family. Embo Rep., 10, 2009
5ERF	Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 分子名称: Polyketide synthase PksL 著者 Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T. 登録日 2015-11-14 公開日 2015-12-23 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
6ERF	Complex of APLF factor and Ku heterodimer bound to DNA 分子名称: Aprataxin and PNK-like factor, DNA (34-MER), DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), ... 著者 Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. 登録日 2017-10-18 公開日 2018-10-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining. Nat.Struct.Mol.Biol., 25, 2018
3ERG	Crystal structure of Gtt2 from Saccharomyces cerevisiae in complex with glutathione sulfnate 分子名称: GLUTATHIONE SULFONIC ACID, Glutathione S-transferase 2 著者 Ma, X.X, Jiang, Y.L, He, Y.X, Chen, Y.X, Zhou, C.Z. 登録日 2008-10-02 公開日 2009-10-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of yeast glutathione-S-transferase Gtt2 reveal a new catalytic type of GST family. Embo Rep., 10, 2009
4ERF	crystal structure of MDM2 (17-111) in complex with compound 29 (AM-8553) 分子名称: E3 ubiquitin-protein ligase Mdm2, {(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(2S,3S)-2-hydroxypentan-3-yl]-3-methyl-2-oxopiperidin-3-yl}acetic acid 著者 Huang, X. 登録日 2012-04-20 公開日 2012-05-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-based design of novel inhibitors of the MDM2-p53 interaction. J.Med.Chem., 55, 2012

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