5SUZ

Domain-swapped dimer of human Dishevelled2 DEP domain: C-centered monoclinic crystal form crystallised from monomeric fraction

Summary for 5SUZ

• Entry DOI: 10.2210/pdb5suz/pdb
• Descriptor: Segment polarity protein dishevelled homolog DVL-2 (2 entities in total)
• Functional Keywords: dishevelled, dep domain, wnt signalling, signaling protein
• Biological source: Homo sapiens (Human)
• Cellular location: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : O14641
• Total number of polymer chains: 2
• Total formula weight: 21685.83

Authors

Renko, M.,Gammons, M.V.,Bienz, M. (deposition date: 2016-08-04, release date: 2016-10-12)

• Primary citation: Gammons, M.V.,Renko, M.,Johnson, C.M.,Rutherford, T.J.,Bienz, M.; Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.; Mol.Cell, 64:92-104, 2016; PubMed: 27692984; DOI: 10.1016/j.molcel.2016.08.026

Experimental method

X-RAY DIFFRACTION (1.84 Å)