2JXZ
Solution Conformation of A Non-Amyloidogenic Analogue of Human Calcitonin in Sodium Dodecyl Sulfate Micelles
Summary for 2JXZ
| Entry DOI | 10.2210/pdb2jxz/pdb |
| Descriptor | Calcitonin (1 entity in total) |
| Functional Keywords | a-helix, amidation, cleavage on pair of basic residues, hormone, secreted |
| Cellular location | Secreted: P01258 |
| Total number of polymer chains | 1 |
| Total formula weight | 3455.89 |
| Authors | Andreotti, G.,Vitale, R.,Avidan-Shpalter, C.,Amodeo, P.,Gazit, E.,Motta, A. (deposition date: 2007-12-03, release date: 2008-11-25, Last modification date: 2011-07-13) |
| Primary citation | Andreotti, G.,Vitale, R.M.,Avidan-Shpalter, C.,Amodeo, P.,Gazit, E.,Motta, A. Converting the highly amyloidogenic human calcitonin into a powerful fibril inhibitor by 3D structure homology with a non-amyloidogenic analogue J.Biol.Chem., 286:2707-2718, 2011 Cited by PubMed: 21078667DOI: 10.1074/jbc.M110.182014 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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