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6FNC
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Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins
分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, CALCIUM ION, ...
著者Bier, D, Ottann, C.
登録日2018-02-02
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins.
Chemistry, 24, 2018
6FN9
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Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins
分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, GLYCEROL, ...
著者Bier, D, Ottmann, C.
登録日2018-02-02
公開日2018-07-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins.
Chemistry, 24, 2018
6FNB
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Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins
分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, CALCIUM ION, ...
著者Bier, D, Ottmann, C.
登録日2018-02-02
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins.
Chemistry, 24, 2018
7QO5
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26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ...
著者Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D.
登録日2021-12-23
公開日2022-03-16
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
7DTO
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Human Annexin A2 with C132-C261 intramolecular disulfide bond
分子名称: Annexin A2
著者He, L.
登録日2021-01-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Human Annexin A2 with C132-C261 intramolecular disulfide bond
To Be Published
8H03
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Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-09-28
公開日2022-11-30
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
8H04
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Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-09-28
公開日2022-11-30
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
5BQC
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BU of 5bqc by Molmil
Crystal structure of Norrin in complex with the cysteine-rich domain of Frizzled 4 and sucrose octasulfate
分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4, ...
著者Chang, T.-H, Hsieh, F.-L, Zebisch, M, Harlos, K, Jones, E.Y.
登録日2015-05-28
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
8IHN
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Cryo-EM structure of the Rpd3S core complex
分子名称: CALCIUM ION, Chromatin modification-related protein EAF3, Histone H3, ...
著者Zhang, Y, Gang, C.
登録日2023-02-23
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme.
Cell Res., 33, 2023
6TWU
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MAGI1_2 complexed with a phosphomimetic 16E6 peptide
分子名称: CALCIUM ION, CITRIC ACID, GLYCEROL, ...
著者Gogl, G, Cousido-Siah, A, Trave, G.
登録日2020-01-13
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 28, 2020
6TWQ
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MAGI1_2 complexed with a 16E6 peptide
分子名称: CALCIUM ION, CITRIC ACID, GLYCEROL, ...
著者Gogl, G, Cousido-Siah, A, Trave, G.
登録日2020-01-13
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 28, 2020
8OKX
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Structure of cGAS in complex with SPSB3-ELOBC
分子名称: Cyclic GMP-AMP synthase, Elongin-B, Elongin-C, ...
著者Xu, P.B, Ablasser, A.
登録日2023-03-29
公開日2024-02-14
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation.
Nature, 627, 2024
3DZU
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BU of 3dzu by Molmil
Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with BVT.13, 9-cis Retinoic Acid and NCOA2 Peptide
分子名称: (9cis)-retinoic acid, 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID, DNA (5'-D(*DCP*DAP*DAP*DAP*DCP*DTP*DAP*DGP*DGP*DTP*DCP*DAP*DAP*DAP*DGP*DGP*DTP*DCP*DAP*DG)-3'), ...
著者Chandra, V, Huang, P, Hamuro, Y, Raghuram, S, Wang, Y, Burris, T.P, Rastinejad, F.
登録日2008-07-30
公開日2008-10-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA.
Nature, 456, 2008
6TWX
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BU of 6twx by Molmil
MAGI1_2 complexed with a phosphorylated 16E6 peptide
分子名称: 16E6 peptide, CALCIUM ION, CITRIC ACID, ...
著者Gogl, G, Cousido-Siah, A, Trave, G.
登録日2020-01-13
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 28, 2020
3E00
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BU of 3e00 by Molmil
Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with GW9662, 9-cis Retinoic Acid and NCOA2 Peptide
分子名称: (9cis)-retinoic acid, 2-chloro-5-nitro-N-phenylbenzamide, DNA (5'-D(*DCP*DAP*DAP*DAP*DCP*DTP*DAP*DGP*DGP*DTP*DCP*DAP*DAP*DAP*DGP*DGP*DTP*DCP*DAP*DG)-3'), ...
著者Chandra, V, Huang, P, Hamuro, Y, Raghuram, S, Wang, Y, Burris, T.P, Rastinejad, F.
登録日2008-07-30
公開日2008-10-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA.
Nature, 456, 2008
3DZY
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BU of 3dzy by Molmil
Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with Rosiglitazone, 9-cis Retinoic Acid and NCOA2 Peptide
分子名称: (9cis)-retinoic acid, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ...
著者Chandra, V, Huang, P, Hamuro, Y, Raghuram, S, Wang, Y, Burris, T.P, Rastinejad, F.
登録日2008-07-30
公開日2008-10-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA.
Nature, 456, 2008
5A5B
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BU of 5a5b by Molmil
Structure of the 26S proteasome-Ubp6 complex
分子名称: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ...
著者Aufderheide, A, Beck, F, Stengel, F, Hartwig, M, Schweitzer, A, Pfeifer, G, Goldberg, A.L, Sakata, E, Baumeister, W, Foerster, F.
登録日2015-06-17
公開日2015-07-22
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (9.5 Å)
主引用文献Structural Characterization of the Interaction of Ubp6 with the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 112, 2015
7K7G
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BU of 7k7g by Molmil
nucleosome and Gal4 complex
分子名称: Centromere DNA-binding protein complex CBF3 subunit B, DNA (147-MER), Histone H2A.1, ...
著者Ruifang, G, Yawen, B.
登録日2020-09-22
公開日2021-03-31
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation.
Nat Commun, 12, 2021
1GAT
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BU of 1gat by Molmil
SOLUTION STRUCTURE OF THE SPECIFIC DNA COMPLEX OF THE ZINC CONTAINING DNA BINDING DOMAIN OF THE ERYTHROID TRANSCRIPTION FACTOR GATA-1 BY MULTIDIMENSIONAL NMR
分子名称: DNA (5'-D(P*AP*GP*AP*TP*AP*AP*AP*C)3'), DNA (5'-D(P*GP*TP*TP*TP*AP*TP*CP*T)-3'), ERYTHROID TRANSCRIPTION FACTOR GATA-1, ...
著者Clore, G.M, Omichinski, J.G, Gronenborn, A.M.
登録日1993-06-28
公開日1993-10-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1.
Science, 261, 1993
1GAU
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BU of 1gau by Molmil
SOLUTION STRUCTURE OF THE SPECIFIC DNA COMPLEX OF THE ZINC CONTAINING DNA BINDING DOMAIN OF THE ERYTHROID TRANSCRIPTION FACTOR GATA-1 BY MULTIDIMENSIONAL NMR
分子名称: DNA (5'-D(P*AP*GP*AP*TP*AP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*TP*AP*TP*CP*T)-3'), ERYTHROID TRANSCRIPTION FACTOR GATA-1
著者Clore, G.M, Omichinski, J.G, Gronenborn, A.M.
登録日1993-06-28
公開日1993-10-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1.
Science, 261, 1993
1HDD
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BU of 1hdd by Molmil
CRYSTAL STRUCTURE OF AN ENGRAILED HOMEODOMAIN-DNA COMPLEX AT 2.8 ANGSTROMS RESOLUTION: A FRAMEWORK FOR UNDERSTANDING HOMEODOMAIN-DNA INTERACTIONS
分子名称: DNA (5'-D(*AP*TP*TP*AP*GP*GP*TP*AP*AP*TP*TP*AP*CP*AP*TP*GP*G P*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*TP*AP*C P*CP*TP*AP*A)-3'), PROTEIN (ENGRAILED HOMEODOMAIN)
著者Kissinger, C.R, Liu, B, Martin-Blanco, E, Kornberg, T.B, Pabo, C.O.
登録日1991-09-16
公開日1992-01-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions.
Cell(Cambridge,Mass.), 63, 1990
1GUX
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RB POCKET BOUND TO E7 LXCXE MOTIF
分子名称: ONCOPROTEIN, RETINOBLASTOMA PROTEIN
著者Lee, J.O, Russo, A.A, Pavletich, N.P.
登録日1997-11-15
公開日1998-12-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7.
Nature, 391, 1998
1H08
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CDK2 in complex with a disubstituted 2, 4-bis anilino pyrimidine CDK4 inhibitor
分子名称: (2R)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OL, (2S)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OL, CELL DIVISION PROTEIN KINASE 2, ...
著者Breault, G.A, Ellston, R.P.A, Green, S, James, S.R, Jewsbury, P.J, Midgley, C.J, Minshull, C.A, Pauptit, R.A, Tucker, J.A, Pease, J.E.
登録日2002-06-11
公開日2003-07-11
最終更新日2011-10-12
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cyclin-Dependent Kinase 4 Inhibitors as a Treatment for Cancer. Part 1: Identification and Optimisation of Substituted 4,6-Bis Anilino Pyrimidines
Bioorg.Med.Chem.Lett., 13, 2003
1HCN
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STRUCTURE OF HUMAN CHORIONIC GONADOTROPIN AT 2.6 ANGSTROMS RESOLUTION FROM MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HUMAN CHORIONIC GONADOTROPIN
著者Wu, H, Lustbader, J.W, Liu, Y, Canfield, R.E, Hendrickson, W.A.
登録日1994-07-01
公開日1994-09-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of human chorionic gonadotropin at 2.6 A resolution from MAD analysis of the selenomethionyl protein.
Structure, 2, 1994
1HDP
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SOLUTION STRUCTURE OF A POU-SPECIFIC HOMEODOMAIN: 3D-NMR STUDIES OF HUMAN B-CELL TRANSCRIPTION FACTOR OCT-2
分子名称: OCT-2 POU HOMEODOMAIN
著者Sivaraja, M, Botfield, M.C, Mueller, M, Jancso, A, Weiss, M.A.
登録日1994-03-08
公開日1995-01-26
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of a POU-specific homeodomain: 3D-NMR studies of human B-cell transcription factor Oct-2.
Biochemistry, 33, 1994

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