6W4S
Structure of apo human ferroportin in lipid nanodisc
Summary for 6W4S
Entry DOI | 10.2210/pdb6w4s/pdb |
EMDB information | 21539 |
Descriptor | Solute carrier family 40 member 1, Fab45D8 Heavy Chain, Fab45D8 Light Chain (3 entities in total) |
Functional Keywords | ferroportin, transporter, iron, hepcidin, transport protein-immune system complex, transport protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 114211.01 |
Authors | Billesboelle, C.B.,Azumaya, C.M.,Gonen, S.,Powers, A.,Kretsch, R.C.,Schneider, S.,Arvedson, T.,Dror, R.O.,Cheng, Y.,Manglik, A. (deposition date: 2020-03-11, release date: 2020-09-09, Last modification date: 2020-11-11) |
Primary citation | Billesbolle, C.B.,Azumaya, C.M.,Kretsch, R.C.,Powers, A.S.,Gonen, S.,Schneider, S.,Arvedson, T.,Dror, R.O.,Cheng, Y.,Manglik, A. Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms. Nature, 586:807-811, 2020 Cited by PubMed: 32814342DOI: 10.1038/s41586-020-2668-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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