1EEG
 
 | | A(GGGG)A HEXAD PAIRING ALIGMENT FOR THE D(G-G-A-G-G-A-G) SEQUENCE | | 分子名称: | DNA (5'-D(*GP*GP*AP*GP*GP*A)-3') | | 著者 | Kettani, A, Gorin, A, Majumdar, A, Hermann, T, Skripkin, E, Zhao, H, Jones, R, Patel, D.J. | | 登録日 | 2000-01-31 | | 公開日 | 2000-04-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A dimeric DNA interface stabilized by stacked A.(G.G.G.G).A hexads and coordinated monovalent cations.
J.Mol.Biol., 297, 2000
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2C5A
 | | GDP-mannose-3', 5' -epimerase (Arabidopsis thaliana),Y174F, with GDP-beta-L-galactose bound in the active site | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, GDP-MANNOSE-3', ... | | 著者 | Major, L.L, Wolucka, B.A, Naismith, J.H. | | 登録日 | 2005-10-26 | | 公開日 | 2005-11-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure and Function of Gdp-Mannose-3',5'-Epimerase: An Enzyme which Performs Three Chemical Reactions at the Same Active Site.
J.Am.Chem.Soc., 127, 2005
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1ESV
 | | COMPLEX BETWEEN LATRUNCULIN A:RABBIT MUSCLE ALPHA ACTIN:HUMAN GELSOLIN DOMAIN 1 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ALPHA ACTIN, CALCIUM ION, ... | | 著者 | Morton, W.M, Ayscough, K.A, McLaughlin, P.J. | | 登録日 | 2000-04-11 | | 公開日 | 2000-07-19 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Latrunculin alters the actin-monomer subunit interface to prevent polymerization.
Nat.Cell Biol., 2, 2000
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2C59
 | | gdp-mannose-3', 5' -epimerase (arabidopsis thaliana), with gdp-alpha-d-mannose and gdp-beta-l-galactose bound in the active site. | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, GDP-MANNOSE-3', ... | | 著者 | Major, L.L, Wolucka, B.A, Naismith, J.H. | | 登録日 | 2005-10-26 | | 公開日 | 2005-11-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and Function of Gdp-Mannose-3',5'-Epimerase: An Enzyme which Performs Three Chemical Reactions at the Same Active Site.
J.Am.Chem.Soc., 127, 2005
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3KMV
 | | Crystal structure of CBM42A from Clostridium thermocellum | | 分子名称: | ACETATE ION, Alpha-L-arabinofuranosidase B, CALCIUM ION, ... | | 著者 | Santos-Silva, T, Alves, V.D, Prates, J.A.M, Fontes, C.M.G.A, Romao, M.J. | | 登録日 | 2009-11-11 | | 公開日 | 2010-08-04 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Family 42 carbohydrate-binding modules display multiple arabinoxylan-binding interfaces presenting different ligand affinities.
Biochim.Biophys.Acta, 1804, 2010
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1G83
 | | CRYSTAL STRUCTURE OF FYN SH3-SH2 | | 分子名称: | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN | | 著者 | Arold, S.T, Ulmer, T.S, Mulhern, T.D, Werner, J.M, Ladbury, J.E, Campbell, I.D, Noble, M.E.M. | | 登録日 | 2000-11-16 | | 公開日 | 2001-05-30 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases.
J.Biol.Chem., 276, 2001
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3IDB
 | | Crystal structure of (108-268)RIIb:C holoenzyme of cAMP-dependent protein kinase | | 分子名称: | MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ... | | 著者 | Brown, S.H.J, Wu, J, Kim, C, Alberto, K, Taylor, S.S. | | 登録日 | 2009-07-20 | | 公開日 | 2009-09-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures.
J.Mol.Biol., 393, 2009
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1JCA
 | | Non-standard Design of Unstable Insulin Analogues with Enhanced Activity | | 分子名称: | ZINC ION, insulin a, insulin b | | 著者 | Weiss, M.A, Wan, Z, Zhao, M, Chu, Y.-C, Nakagawa, S.H, Burke, G.T, Jia, W, Hellmich, R, Katsoyannis, P.G. | | 登録日 | 2001-06-08 | | 公開日 | 2001-06-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor.
J.Mol.Biol., 315, 2002
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3IDC
 | | Crystal structure of (102-265)RIIb:C holoenzyme of cAMP-dependent protein kinase | | 分子名称: | MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ... | | 著者 | Brown, S.H.J, Wu, J, Kim, C, Alberto, K, Taylor, S.S. | | 登録日 | 2009-07-20 | | 公開日 | 2009-09-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures.
J.Mol.Biol., 393, 2009
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2K6L
 | | The solution structure of XACb0070 from Xanthonomas axonopodis pv citri reveals this new protein is a member of the RHH family of transcriptional repressors | | 分子名称: | Putative uncharacterized protein | | 著者 | Gallo, M, Cicero, D.O, Amata, I, Eliseo, T, Paci, M, Spisni, A, Ferrari, E, Pertinhez, T.A, Farah, C.S. | | 登録日 | 2008-07-11 | | 公開日 | 2009-06-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure reveals that XACb0070 from the plant pathogen Xanthomonas citri belongs to the RHH superfamily of bacterial DNA-binding proteins
To be Published
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5AJJ
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3SS1
 | | Clostridium difficile toxin A (TcdA) glucolsyltransferase domain | | 分子名称: | MANGANESE (II) ION, Toxin A | | 著者 | Pruitt, R.N, Chumbler, N.M, Farrow, M.A, Seeback, S.A, Friedman, D.B, Spiller, B.W, Lacy, D.B. | | 登録日 | 2011-07-07 | | 公開日 | 2012-02-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Structural Determinants of Clostridium difficile Toxin A Glucosyltransferase Activity.
J.Biol.Chem., 287, 2012
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3TT9
 | | Crystal structure of the stable degradation fragment of human plakophilin 2 isoform a (PKP2a) C752R variant | | 分子名称: | GLYCEROL, Plakophilin-2 | | 著者 | Schuetz, A, Roske, Y, Gerull, B, Heinemann, U. | | 登録日 | 2011-09-14 | | 公開日 | 2012-08-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations.
Circ Cardiovasc Genet, 5, 2012
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5BRW
 | | Catalytic Improvement of an Artificial Metalloenzyme by Computational Design | | 分子名称: | ACETATE ION, Carbonic anhydrase 2, SULFATE ION, ... | | 著者 | Heinisch, T, Pellizzoni, M, Duerrenberger, M, Tinberg, C.E, Koehler, V, Klehr, J, Haeussinger, D, Baker, D, Ward, T.R. | | 登録日 | 2015-06-01 | | 公開日 | 2015-06-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Improving the Catalytic Performance of an Artificial Metalloenzyme by Computational Design.
J.Am.Chem.Soc., 137, 2015
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1W4I
 | | Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions | | 分子名称: | PYRUVATE DEHYDROGENASE E2 | | 著者 | Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R. | | 登録日 | 2004-07-23 | | 公開日 | 2005-07-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
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1W4E
 | | Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions | | 分子名称: | DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE | | 著者 | Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R. | | 登録日 | 2004-07-23 | | 公開日 | 2005-07-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
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1W4G
 | | Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state folding transitions | | 分子名称: | DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE | | 著者 | Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R. | | 登録日 | 2004-07-23 | | 公開日 | 2005-07-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
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3SL9
 | | X-ray structure of Beta catenin in complex with Bcl9 | | 分子名称: | 1,2-ETHANEDIOL, B-cell CLL/lymphoma 9 protein, Catenin beta-1, ... | | 著者 | Gupta, D, Bienz, M. | | 登録日 | 2011-06-24 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
Nat Commun, 3, 2012
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3SLA
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1W4F
 | | Peripheral-subunit from mesophilic, thermophilic and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions | | 分子名称: | DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE | | 著者 | Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Fersht, A.R. | | 登録日 | 2004-07-23 | | 公開日 | 2005-07-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
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5TOI
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4DXT
 | | Human SUN2 (AA 522-717) | | 分子名称: | POTASSIUM ION, SUN domain-containing protein 2 | | 著者 | Sosa, B, Schwartz, T.U. | | 登録日 | 2012-02-28 | | 公開日 | 2012-06-06 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins.
Cell(Cambridge,Mass.), 149, 2012
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2X0V
 | | STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 4-(trifluoromethyl)benzene-1,2-diamine | | 分子名称: | 4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE, CELLULAR TUMOR ANTIGEN P53, ZINC ION | | 著者 | Basse, N, Kaar, J.L, Joerger, A.C, Fersht, A.R. | | 登録日 | 2009-12-17 | | 公開日 | 2010-01-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant.
Chem.Biol., 17, 2010
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2VUK
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5CR5
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