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3SLA

X-ray structure of first four repeats of human beta-catenin

Summary for 3SLA
Entry DOI10.2210/pdb3sla/pdb
Related2GL7 3SL9
DescriptorCatenin beta-1, GLYCEROL, SODIUM ION, ... (4 entities in total)
Functional Keywordsbeta catenin, armadillo repeat, key component of the wnt signaling pathway, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P35222
Total number of polymer chains5
Total formula weight92479.47
Authors
Gupta, D.,Bienz, M. (deposition date: 2011-06-24, release date: 2012-02-29, Last modification date: 2024-02-28)
Primary citationde la Roche, M.,Rutherford, T.J.,Gupta, D.,Veprintsev, D.B.,Saxty, B.,Freund, S.M.,Bienz, M.
An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
Nat Commun, 3:680-680, 2012
Cited by
PubMed: 22353711
DOI: 10.1038/ncomms1680
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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