3SLA
X-ray structure of first four repeats of human beta-catenin
Summary for 3SLA
Entry DOI | 10.2210/pdb3sla/pdb |
Related | 2GL7 3SL9 |
Descriptor | Catenin beta-1, GLYCEROL, SODIUM ION, ... (4 entities in total) |
Functional Keywords | beta catenin, armadillo repeat, key component of the wnt signaling pathway, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P35222 |
Total number of polymer chains | 5 |
Total formula weight | 92479.47 |
Authors | |
Primary citation | de la Roche, M.,Rutherford, T.J.,Gupta, D.,Veprintsev, D.B.,Saxty, B.,Freund, S.M.,Bienz, M. An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid. Nat Commun, 3:680-680, 2012 Cited by PubMed: 22353711DOI: 10.1038/ncomms1680 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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