3SLA
X-ray structure of first four repeats of human beta-catenin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007155 | biological_process | cell adhesion |
| A | 0045296 | molecular_function | cadherin binding |
| B | 0007155 | biological_process | cell adhesion |
| B | 0045296 | molecular_function | cadherin binding |
| C | 0007155 | biological_process | cell adhesion |
| C | 0045296 | molecular_function | cadherin binding |
| D | 0007155 | biological_process | cell adhesion |
| D | 0045296 | molecular_function | cadherin binding |
| E | 0007155 | biological_process | cell adhesion |
| E | 0045296 | molecular_function | cadherin binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL A 1 |
| Chain | Residue |
| A | LYS181 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 2 |
| Chain | Residue |
| A | LYS242 |
| A | SER246 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 4 |
| Chain | Residue |
| A | VAL173 |
| A | GLN177 |
| E | ALA272 |
| E | LEU275 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 7 |
| Chain | Residue |
| A | LYS270 |
| A | MET271 |
| A | ARG274 |
| D | ALA152 |
| D | GLU155 |
| A | GLY268 |
| A | ALA269 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL D 3 |
| Chain | Residue |
| D | THR205 |
| D | ASN206 |
| D | LYS242 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL D 5 |
| Chain | Residue |
| A | LEU229 |
| A | GLU267 |
| D | ASP162 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL E 6 |
| Chain | Residue |
| E | PRO247 |
| E | ASP249 |
| E | THR289 |
| E | ASN290 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL E 8 |
| Chain | Residue |
| E | MET189 |
| E | GLU226 |
| E | LEU229 |
| E | LYS233 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA E 1 |
| Chain | Residue |
| E | HIS223 |
| E | ASN261 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA E 2 |
| Chain | Residue |
| E | THR257 |
| E | HIS260 |
| E | ASN261 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 160 |
| Details | Repeat: {"description":"ARM 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 205 |
| Details | Repeat: {"description":"ARM 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 205 |
| Details | Repeat: {"description":"ARM 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 88 |
| Details | Region: {"description":"Interaction with BCL9","evidences":[{"source":"PubMed","id":"17052462","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by FYN and PTK6","evidences":[{"source":"PubMed","id":"12640114","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20026641","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 5 |
| Details | Modified residue: {"description":"Phosphoserine; by CDK5","evidences":[{"source":"PubMed","id":"17009320","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 5 |
| Details | Modified residue: {"description":"Phosphoserine; by CDK5","evidences":[{"source":"PubMed","id":"17009320","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
