1G83

CRYSTAL STRUCTURE OF FYN SH3-SH2

Summary for 1G83

DescriptorPROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (2 entities in total)
Functional Keywordsbeta barrel, antiparallel beta sheet, alpha helix, 3-10 helix, transferase
Biological sourceHomo sapiens (human)
Cellular locationCell membrane P06241
Total number of polymer chains2
Total molecular weight37821.86
Authors
Arold, S.T.,Ulmer, T.S.,Mulhern, T.D.,Werner, J.M.,Ladbury, J.E.,Campbell, I.D.,Noble, M.E.M. (deposition date: 2000-11-16, release date: 2001-05-30, Last modification date: 2011-07-13)
Primary citation
Arold, S.T.,Ulmer, T.S.,Mulhern, T.D.,Werner, J.M.,Ladbury, J.E.,Campbell, I.D.,Noble, M.E.
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases.
J.Biol.Chem., 276:17199-17205, 2001
PubMed: 11278857 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M011185200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.292222.2%5.8%1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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