3SL9

X-ray structure of Beta catenin in complex with Bcl9

Summary for 3SL9

• Entry DOI: 10.2210/pdb3sl9/pdb
• Related: 2GL7 3SLA
• Descriptor: Catenin beta-1, B-cell CLL/lymphoma 9 protein, 1,2-ETHANEDIOL, ... (7 entities in total)
• Functional Keywords: armadillo repeat, components of the wnt signaling pathway, beta catenin, signaling protein, protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P35222; Nucleus (By similarity): O00512
• Total number of polymer chains: 8
• Total formula weight: 99549.13

Authors

Gupta, D.,Bienz, M. (deposition date: 2011-06-24, release date: 2012-02-29, Last modification date: 2023-09-13)

• Primary citation: de la Roche, M.,Rutherford, T.J.,Gupta, D.,Veprintsev, D.B.,Saxty, B.,Freund, S.M.,Bienz, M.; An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.; Nat Commun, 3:680-680, 2012; PubMed: 22353711; DOI: 10.1038/ncomms1680

Experimental method

X-RAY DIFFRACTION (2.2 Å)