2C59

gdp-mannose-3', 5' -epimerase (arabidopsis thaliana), with gdp-alpha-d-mannose and gdp-beta-l-galactose bound in the active site.

Summary for 2C59

Entry DOI	10.2210/pdb2c59/pdb
Related	2C54 2C5A 2C5E
Descriptor	GDP-MANNOSE-3', 5'-EPIMERASE, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, GUANOSINE-5'-DIPHOSPHATE-BETA-L-GALACTOSE, ... (7 entities in total)
Functional Keywords	3' 5'-epimerase, short chain dehydratase/reductase, gdp-mannose, gdp-gulose, gdp-galactose, keto intermediate, vitamin c, ascorbate biosynthesis, isomerase
Biological source	Arabidopsis thaliana
Total number of polymer chains	2
Total formula weight	90212.86
Authors	Major, L.L.,Wolucka, B.A.,Naismith, J.H. (deposition date: 2005-10-26, release date: 2005-11-14, Last modification date: 2023-12-13)
Primary citation	Major, L.L.,Wolucka, B.A.,Naismith, J.H. Structure and Function of Gdp-Mannose-3',5'-Epimerase: An Enzyme which Performs Three Chemical Reactions at the Same Active Site. J.Am.Chem.Soc., 127:18309-, 2005 Cited by PubMed: 16366586 DOI: 10.1021/JA056490I PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation