Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005829 | cellular_component | cytosol |
| A | 0009536 | cellular_component | plastid |
| A | 0010494 | cellular_component | cytoplasmic stress granule |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016854 | molecular_function | racemase and epimerase activity |
| A | 0019853 | biological_process | L-ascorbic acid biosynthetic process |
| A | 0047918 | molecular_function | GDP-mannose 3,5-epimerase activity |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0005829 | cellular_component | cytosol |
| B | 0009536 | cellular_component | plastid |
| B | 0010494 | cellular_component | cytoplasmic stress granule |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016854 | molecular_function | racemase and epimerase activity |
| B | 0019853 | biological_process | L-ascorbic acid biosynthetic process |
| B | 0047918 | molecular_function | GDP-mannose 3,5-epimerase activity |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE GDD A1377 |
| Chain | Residue |
| A | MET102 |
| A | ASN203 |
| A | GLU216 |
| A | LYS217 |
| A | ALA218 |
| A | ALA221 |
| A | PHE222 |
| A | LYS225 |
| A | TRP236 |
| A | GLN241 |
| A | ARG243 |
| A | GLY103 |
| A | MET277 |
| A | PRO300 |
| A | GLU301 |
| A | ARG306 |
| A | SER356 |
| A | HOH2217 |
| A | HOH2295 |
| A | HOH2380 |
| A | GLY104 |
| A | MET105 |
| A | ILE108 |
| A | SER143 |
| A | ALA144 |
| A | CYS145 |
| A | TYR174 |
| site_id | AC2 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE GDC A1378 |
| Chain | Residue |
| A | MET102 |
| A | GLY103 |
| A | GLY104 |
| A | MET105 |
| A | ILE108 |
| A | SER143 |
| A | CYS145 |
| A | TYR174 |
| A | PHE201 |
| A | HIS202 |
| A | ASN203 |
| A | GLU216 |
| A | LYS217 |
| A | ALA218 |
| A | ALA221 |
| A | PHE222 |
| A | LYS225 |
| A | TRP236 |
| A | GLN241 |
| A | ARG243 |
| A | MET277 |
| A | PRO300 |
| A | GLU301 |
| A | ARG306 |
| A | SER356 |
| A | NAD1379 |
| A | HOH2217 |
| A | HOH2295 |
| A | HOH2380 |
| site_id | AC3 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE NAD A1379 |
| Chain | Residue |
| A | GLY34 |
| A | GLY36 |
| A | GLY37 |
| A | PHE38 |
| A | ILE39 |
| A | ASP58 |
| A | TRP59 |
| A | LYS60 |
| A | VAL77 |
| A | ASP78 |
| A | LEU79 |
| A | ARG80 |
| A | LEU98 |
| A | ALA99 |
| A | ALA100 |
| A | MET102 |
| A | ILE122 |
| A | ALA141 |
| A | SER142 |
| A | SER143 |
| A | TYR174 |
| A | LYS178 |
| A | PHE201 |
| A | ASN203 |
| A | ILE204 |
| A | LYS217 |
| A | GDC1378 |
| A | HOH2097 |
| A | HOH2381 |
| A | HOH2382 |
| A | HOH2383 |
| A | HOH2384 |
| A | HOH2385 |
| A | HOH2386 |
| A | HOH2387 |
| A | HOH2388 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE BTB B1376 |
| Chain | Residue |
| B | GLU90 |
| B | GLY91 |
| B | HOH2141 |
| B | HOH2448 |
| A | FMT1382 |
| A | HOH2319 |
| B | LYS29 |
| B | TYR53 |
| B | ILE55 |
| B | GLU73 |
| B | LYS87 |
| site_id | AC5 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE GDD B1377 |
| Chain | Residue |
| B | MET102 |
| B | GLY103 |
| B | GLY104 |
| B | MET105 |
| B | ILE108 |
| B | SER143 |
| B | CYS145 |
| B | TYR174 |
| B | PHE201 |
| B | HIS202 |
| B | ASN203 |
| B | GLU216 |
| B | LYS217 |
| B | ALA218 |
| B | ALA221 |
| B | PHE222 |
| B | LYS225 |
| B | MET235 |
| B | TRP236 |
| B | GLN241 |
| B | ARG243 |
| B | MET277 |
| B | PRO300 |
| B | GLU301 |
| B | SER356 |
| B | HOH2449 |
| B | HOH2450 |
| B | HOH2451 |
| site_id | AC6 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE GDC B1378 |
| Chain | Residue |
| B | MET102 |
| B | GLY103 |
| B | GLY104 |
| B | MET105 |
| B | ILE108 |
| B | SER143 |
| B | CYS145 |
| B | TYR174 |
| B | PHE201 |
| B | ASN203 |
| B | GLU216 |
| B | LYS217 |
| B | ALA218 |
| B | ALA221 |
| B | PHE222 |
| B | LYS225 |
| B | MET235 |
| B | TRP236 |
| B | GLN241 |
| B | ARG243 |
| B | MET277 |
| B | PRO300 |
| B | GLU301 |
| B | ARG306 |
| B | SER356 |
| B | NAD1380 |
| B | HOH2449 |
| B | HOH2450 |
| B | HOH2451 |
| site_id | AC7 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE NAD B1380 |
| Chain | Residue |
| B | GLY34 |
| B | GLY36 |
| B | GLY37 |
| B | PHE38 |
| B | ILE39 |
| B | ASP58 |
| B | TRP59 |
| B | LYS60 |
| B | VAL77 |
| B | ASP78 |
| B | LEU79 |
| B | ARG80 |
| B | LEU98 |
| B | ALA99 |
| B | ALA100 |
| B | MET102 |
| B | ILE122 |
| B | ALA141 |
| B | SER142 |
| B | SER143 |
| B | TYR174 |
| B | LYS178 |
| B | PHE201 |
| B | ASN203 |
| B | ILE204 |
| B | LYS217 |
| B | ARG371 |
| B | GDC1378 |
| B | HOH2152 |
| B | HOH2156 |
| B | HOH2282 |
| B | HOH2452 |
| B | HOH2453 |
| B | HOH2454 |
| B | HOH2455 |
| B | HOH2456 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FMT A1380 |
| Chain | Residue |
| A | LYS212 |
| A | GLY213 |
| A | ARG224 |
| A | LEU352 |
| A | TYR353 |
| A | SER355 |
| A | LYS357 |
| A | HOH2218 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A1381 |
| Chain | Residue |
| A | PHE150 |
| B | PRO167 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT A1382 |
| Chain | Residue |
| A | GLU18 |
| A | ARG257 |
| A | GLY318 |
| A | TRP319 |
| B | LYS29 |
| B | BTB1376 |
| B | HOH2147 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT B1371 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT B1372 |
| Chain | Residue |
| B | ARG215 |
| B | GLN362 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT B1373 |
| Chain | Residue |
| B | SER229 |
| B | THR230 |
| B | ASP231 |
| B | ARG232 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT B1374 |
| Chain | Residue |
| A | VAL77 |
| A | ASP78 |
| A | ASN84 |
| A | GLY368 |
| A | SER369 |
| B | HIS295 |
| B | HOH2444 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT B1375 |
| Chain | Residue |
| A | PRO167 |
| B | PHE150 |
| B | HOH2445 |
| B | HOH2446 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 60 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16366586","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 22 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19376835","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | SER143 | |
| A | TYR174 | |
| A | LYS178 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | SER143 | |
| B | TYR174 | |
| B | LYS178 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | SER142 | |
| A | TYR174 | |
| A | LYS178 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | SER142 | |
| B | TYR174 | |
| B | LYS178 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | SER143 | |
| A | TYR174 | |
| A | ASN119 | |
| A | LYS178 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | SER143 | |
| B | TYR174 | |
| B | ASN119 | |
| B | LYS178 | |
| site_id | CSA7 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | TYR174 | |
| A | LYS178 | |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | TYR174 | |
| B | LYS178 | |
