2C5A
GDP-mannose-3', 5' -epimerase (Arabidopsis thaliana),Y174F, with GDP-beta-L-galactose bound in the active site
Summary for 2C5A
Entry DOI | 10.2210/pdb2c5a/pdb |
Related | 2C54 2C59 2C5E |
Descriptor | GDP-MANNOSE-3', 5'-EPIMERASE, GUANOSINE-5'-DIPHOSPHATE-BETA-L-GALACTOSE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (6 entities in total) |
Functional Keywords | 3' 5'-epimerase, short chain dehydratase/reductase, gdp-mannose, gdp-gulose, gdp-galactose, keto intermediate, vitamin c, sdr, ascorbate biosynthesis, isomerase, nad |
Biological source | Arabidopsis thaliana (MOUSE-EAR CRESS) |
Total number of polymer chains | 2 |
Total formula weight | 89384.40 |
Authors | Major, L.L.,Wolucka, B.A.,Naismith, J.H. (deposition date: 2005-10-26, release date: 2005-11-14, Last modification date: 2023-12-13) |
Primary citation | Major, L.L.,Wolucka, B.A.,Naismith, J.H. Structure and Function of Gdp-Mannose-3',5'-Epimerase: An Enzyme which Performs Three Chemical Reactions at the Same Active Site. J.Am.Chem.Soc., 127:18309-, 2005 Cited by PubMed: 16366586DOI: 10.1021/JA056490I PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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