2C5A

GDP-mannose-3', 5' -epimerase (Arabidopsis thaliana),Y174F, with GDP-beta-L-galactose bound in the active site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	GDP-MANNOSE-3', 5'-EPIMERASE	polymer	379	42927.6	2	UniProt (Q93VR3) Pfam (PF01370)	Arabidopsis thaliana (MOUSE-EAR CRESS)	GDP-MAN 3,5-EPIMERASE
2	C, Q (A, B)	GUANOSINE-5'-DIPHOSPHATE-BETA-L-GALACTOSE	non-polymer		605.3	2	Chemie (GDC)
3	D, R (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
4	E, F, G, H, I... (A, B)	FORMIC ACID	non-polymer		46.0	17	Chemie (FMT)
5	X (B)	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	1	Chemie (BTB)
6	Y, Z (A, B)	water	water		18.0	1018	Chemie (HOH)

Sequence modifications

A, B: -1 - 0 (PDB: 2C5A)
A, B: 1 - 377 (UniProt: Q93VR3)

PDB	External Database	Details
Phe 174	Tyr 174	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	85855.2
Non-Polymers*	Number of molecules	22
	Total formula weight	3529.2
All*	Total formula weight	89384.4

*Water molecules are not included.