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7R7A
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State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model
分子名称: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
著者Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
登録日2021-06-24
公開日2022-11-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7V2Y
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BU of 7v2y by Molmil
cryo-EM structure of yeast THO complex with Sub2
分子名称: ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2, ...
著者Chen, C, Tan, M, Wu, Z, Wu, J, Lei, M.
登録日2021-08-10
公開日2022-07-27
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural and functional insights into R-loop prevention and mRNA export by budding yeast THO-Sub2 complex.
Sci Bull (Beijing), 66, 2021
7V6B
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BU of 7v6b by Molmil
Structure of the Dicer-2-R2D2 heterodimer
分子名称: Dicer-2, isoform A, R2D2
著者Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O.
登録日2021-08-20
公開日2022-03-23
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.
Nature, 607, 2022
7V6C
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BU of 7v6c by Molmil
Structure of the Dicer-2-R2D2 heterodimer bound to small RNA duplex
分子名称: Dicer-2, isoform A, R2D2, ...
著者Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O.
登録日2021-08-20
公開日2022-03-23
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.
Nature, 607, 2022
7PLI
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DEAD-box helicase DbpA bound to single stranded RNA and ADP/BeF3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DbpA, BERYLLIUM TRIFLUORIDE ION, ...
著者Wurm, J.P.
登録日2021-08-31
公開日2022-09-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA.
Rna, 29, 2023
7PMQ
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BU of 7pmq by Molmil
DEAD-box helicase DbpA in the active conformation bound to a hairpin loop RNA and ADP/BeF3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DbpA, BERYLLIUM TRIFLUORIDE ION, ...
著者Wurm, J.P.
登録日2021-09-02
公開日2022-09-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA.
Rna, 29, 2023
7PMM
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DEAD-box helicase DbpA in the active conformation bound to a ss/dsRNA junction and ADP/BeF3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DbpA, BERYLLIUM TRIFLUORIDE ION, ...
著者Wurm, J.P.
登録日2021-09-02
公開日2022-09-14
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA.
Rna, 29, 2023
7VG2
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BU of 7vg2 by Molmil
Cryo-EM structure of Arabidopsis DCL3 in complex with a 40-bp RNA
分子名称: CALCIUM ION, Dicer-like 3, TAS1a forward strand (5'-phosphorylation), ...
著者Wang, Q, Du, J.
登録日2021-09-14
公開日2021-10-27
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation.
Science, 374, 2021
7VG3
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Cryo-EM structure of Arabidopsis DCL3 in complex with a 30-bp RNA
分子名称: CALCIUM ION, Dicer-like 3, TAS1a RNA forward strand (5'-phosphorylated), ...
著者Wang, Q, Du, J.
登録日2021-09-14
公開日2021-10-27
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation.
Science, 374, 2021
7PQ0
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BU of 7pq0 by Molmil
Crystal structure of the Burkholderia Lethal Factor 1 (BLF1) C94S inactive mutant in complex with human eIF4A - Crystal form B
分子名称: Burkholderia Lethal Factor 1 (BLF1), Eukaryotic initiation factor 4A-I
著者Mobbs, G.W, Aziz, A.A, Dix, S.R, Blackburn, G.M, Sedelnikova, S.E, Minshull, T.C, Dickman, M.J, Baker, P.J, Nathan, S, Firdaus-Raih, M, Rice, D.W.
登録日2021-09-15
公開日2022-04-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1.
Commun Biol, 5, 2022
7PPZ
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Crystal structure of the Burkholderia Lethal Factor 1 (BLF1) C94S inactive mutant in complex with human eIF4A - Crystal form A
分子名称: Burkholderia Lethal Factor 1 (BLF1), Eukaryotic initiation factor 4A-I
著者Mobbs, G.W, Aziz, A.A, Dix, S.R, Blackburn, G.M, Sedelnikova, S.E, Minshull, T.C, Dickman, M.J, Baker, P.J, Nathan, S, Firdaus-Raih, M, Rice, D.W.
登録日2021-09-15
公開日2022-04-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1.
Commun Biol, 5, 2022
7S7B
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BU of 7s7b by Molmil
Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1)
分子名称: Exosome RNA helicase MTR4, RNA (46-MER), RNA-binding protein 7, ...
著者Puno, M.R, Lima, C.D.
登録日2021-09-15
公開日2022-06-15
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.06 Å)
主引用文献Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Cell, 185, 2022
7S7C
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BU of 7s7c by Molmil
Human Nuclear Exosome Targeting (NEXT) complex bound to RNA (substrate 2)
分子名称: Exosome RNA helicase MTR4, RNA (30-MER), RNA-binding protein 7, ...
著者Puno, M.R, Lima, C.D.
登録日2021-09-15
公開日2022-06-15
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Cell, 185, 2022
7PX3
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BU of 7px3 by Molmil
Structure of U5 snRNP assembly and recycling factor TSSC4 in complex with BRR2 and Jab1 domain of PRPF8
分子名称: Pre-mRNA-processing-splicing factor 8, Protein TSSC4, U5 small nuclear ribonucleoprotein 200 kDa helicase
著者Bergfort, A, Kuropka, B, Ilik, I.A, Freund, C, Aktas, T, Hilal, T, Weber, G, Wahl, M.C.
登録日2021-10-07
公開日2022-01-26
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
7VPX
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BU of 7vpx by Molmil
The cryo-EM structure of the human pre-A complex
分子名称: 5SS, DnaJ homolog subfamily C member 8, PHD finger-like domain-containing protein 5A, ...
著者Zhang, X, Zhan, X, Shi, Y.
登録日2021-10-18
公開日2023-05-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into branch site proofreading by human spliceosome.
Nat.Struct.Mol.Biol., 2024
7Q3L
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BU of 7q3l by Molmil
Human 17S U2 snRNP 5' domain
分子名称: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ...
著者Tholen, J, Galej, W.P.
登録日2021-10-28
公開日2022-03-30
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structural basis of branch site recognition by the human spliceosome.
Science, 375, 2022
7SSG
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BU of 7ssg by Molmil
Mfd DNA complex
分子名称: DNA (5'-D(P*TP*GP*GP*CP*GP*GP*CP*GP*AP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*GP*CP*CP*TP*CP*GP*CP*TP*GP*CP*CP*A)-3'), Transcription-repair-coupling factor
著者Oakley, A.J, Xu, Z.-Q.
登録日2021-11-11
公開日2022-05-25
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Mechanism of transcription modulation by the transcription-repair coupling factor.
Nucleic Acids Res., 50, 2022
7W0B
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BU of 7w0b by Molmil
Dicer2-LoqsPD complex at apo status
分子名称: Dicer-2, isoform A, Loquacious, ...
著者Su, S, Wang, J, Wang, H.W, Ma, J.
登録日2021-11-18
公開日2022-04-27
最終更新日2022-07-27
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0E
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BU of 7w0e by Molmil
dmDicer2-LoqsPD-dsRNA Active-dicing status
分子名称: ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ...
著者Su, S, Wang, J, Wang, H.W, Ma, J.
登録日2021-11-18
公開日2022-04-27
最終更新日2022-07-27
実験手法ELECTRON MICROSCOPY (4.03 Å)
主引用文献Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0D
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BU of 7w0d by Molmil
Dicer2-LoqsPD-dsRNA complex at mid-translocation state
分子名称: ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ...
著者Su, S, Wang, J, Wang, H.W, Ma, J.
登録日2021-11-18
公開日2022-04-27
最終更新日2022-07-27
実験手法ELECTRON MICROSCOPY (4.18 Å)
主引用文献Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0F
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BU of 7w0f by Molmil
dmDicer2-LoqsPD-dsRNA Post-dicing status
分子名称: Dicer-2, isoform A, Loquacious, ...
著者Su, S, Wang, J, Wang, H.W, Ma, J.
登録日2021-11-18
公開日2022-04-27
最終更新日2022-07-27
実験手法ELECTRON MICROSCOPY (4.55 Å)
主引用文献Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0A
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dmDicer2-LoqsPD-dsRNA Dimer status
分子名称: Dicer-2, isoform A, Loquacious, ...
著者Su, S, Wang, J, Wang, H.W, Ma, J.
登録日2021-11-18
公開日2022-04-27
最終更新日2022-07-27
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7W0C
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BU of 7w0c by Molmil
Dicer2-Loqs-PD-dsRNA complex at early-translocation state
分子名称: ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ...
著者Su, S, Wang, J, Wang, H.W, Ma, J.
登録日2021-11-18
公開日2022-04-27
最終更新日2022-07-27
実験手法ELECTRON MICROSCOPY (3.93 Å)
主引用文献Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
7QDR
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BU of 7qdr by Molmil
Apo human SKI complex in the closed state
分子名称: Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61
著者Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E.
登録日2021-11-29
公開日2022-02-02
最終更新日2022-03-02
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism.
Mol.Cell, 82, 2022
7W59
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The cryo-EM structure of human pre-C*-I complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2021-11-29
公開日2022-06-22
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022

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