7UQZ
| Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1 D52A strain | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | 著者 | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | 登録日 | 2022-04-20 | 公開日 | 2023-03-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.44 Å) | 主引用文献 | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
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7ZMZ
| Engineered Interleukin 2 bound to CD25 receptor | 分子名称: | Interleukin-2, Interleukin-2 receptor subunit alpha | 著者 | Fyfe, P.K, Moraga, I, Gaggero, S, Mitra, S. | 登録日 | 2022-04-20 | 公開日 | 2022-12-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein. Sci Immunol, 7, 2022
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7UQU
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7UQR
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7ZN7
| Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and rat STAT2 CCD | 分子名称: | B27a, DNA damage-binding protein 1, Signal transducer and activator of transcription, ... | 著者 | Lauer, S, Spahn, C.M.T, Schwefel, D. | 登録日 | 2022-04-20 | 公開日 | 2022-11-09 | 最終更新日 | 2023-03-15 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor. Embo J., 42, 2023
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7XKO
| F1 domain of epsilon C-terminal domain deleted FoF1 from Bacillus PS3,state1,nucleotide depeleted | 分子名称: | ATP synthase gamma chain, ATP synthase subunit alpha, ATP synthase subunit beta, ... | 著者 | Nakano, A, Kishikawa, J, Nakanishi, A, Mitsuoka, K, Yokoyama, K. | 登録日 | 2022-04-20 | 公開日 | 2022-09-21 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of unisite catalysis of bacterial F 0 F 1 -ATPase. Pnas Nexus, 1, 2022
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7XKQ
| F1 domain of FoF1-ATPase with the down form of epsilon subunit from Bacillus PS3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | 著者 | Nakano, A, Kishikawa, J, Nakanishi, A, Mitsuoka, K, Yokoyama, K. | 登録日 | 2022-04-20 | 公開日 | 2022-09-21 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of unisite catalysis of bacterial F 0 F 1 -ATPase. Pnas Nexus, 1, 2022
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7XKR
| F1 domain of FoF1-ATPase with the up form of epsilon subunit from Bacillus PS3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | 著者 | Nakano, A, Kishikawa, J, Nakanishi, A, Mitsuoka, K, Yokoyama, K. | 登録日 | 2022-04-20 | 公開日 | 2022-09-21 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural basis of unisite catalysis of bacterial F 0 F 1 -ATPase. Pnas Nexus, 1, 2022
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7XKP
| F1 domain of epsilon C-terminal domain deleted FoF1 from Bacillus PS3,state1,unisite condition | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP synthase gamma chain, ATP synthase subunit alpha, ... | 著者 | Nakano, A, Kishikawa, J, Nakanishi, A, Mitsuoka, K, Yokoyama, K. | 登録日 | 2022-04-20 | 公開日 | 2022-09-21 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of unisite catalysis of bacterial F 0 F 1 -ATPase. Pnas Nexus, 1, 2022
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7XKT
| Human Cx36/GJD2 (BRIL-fused mutant) gap junction channel in detergents at 2.2 Angstroms resolution | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Cho, H.J, Lee, S.N, Jeong, H, Ryu, B, Lee, H.J, Woo, J.S, Lee, H.H. | 登録日 | 2022-04-20 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XKJ
| Kras-G12D-GDP-MRTX1133 by FIB-MicroED | 分子名称: | 4-(4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidin-7-yl)-5-ethynyl-6-fluoronaphthalen-2-ol, GUANOSINE-5'-DIPHOSPHATE, KRAS proto-oncogene, ... | 著者 | Li, X.M. | 登録日 | 2022-04-19 | 公開日 | 2023-08-02 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (3 Å) | 主引用文献 | Kras-G12D-GDP-MRTX1133 by FIB-MicroED To Be Published
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7UQB
| Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1-D52A strain with AlF4 | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | 著者 | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | 登録日 | 2022-04-19 | 公開日 | 2023-03-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | 主引用文献 | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
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7XKH
| Nucleotide-depleted F1 domain of FoF1-ATPase from Bacillus PS3, state1 | 分子名称: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit alpha, ... | 著者 | Nakano, A, Kishikawa, J, Nakanishi, A, Mitsuoka, K, Yokoyama, K. | 登録日 | 2022-04-19 | 公開日 | 2022-09-21 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of unisite catalysis of bacterial F 0 F 1 -ATPase. Pnas Nexus, 1, 2022
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7UQK
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7UQJ
| Cryo-EM structure of the S. cerevisiae chromatin remodeler Yta7 hexamer bound to ATPgS and histone H3 tail in state II | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATPase histone chaperone YTA7, Histone H3, ... | 著者 | Wang, F, Feng, X, Li, H. | 登録日 | 2022-04-19 | 公開日 | 2023-02-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | The Saccharomyces cerevisiae Yta7 ATPase hexamer contains a unique bromodomain tier that functions in nucleosome disassembly. J.Biol.Chem., 299, 2022
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7UQI
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7XKE
| Cryo-EM structure of DHEA-ADGRG2-FL-Gs complex | 分子名称: | 3-BETA-HYDROXY-5-ANDROSTEN-17-ONE, Adhesion G-protein coupled receptor G2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Guo, S.C, Xiao, P, Lin, H, Sun, J.P, Yu, X. | 登録日 | 2022-04-19 | 公開日 | 2022-08-10 | 最終更新日 | 2023-03-15 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structures of the ADGRG2-G s complex in apo and ligand-bound forms. Nat.Chem.Biol., 18, 2022
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7XKF
| Cryo-EM structure of DHEA-ADGRG2-BT-Gs complex at lower state | 分子名称: | 3-BETA-HYDROXY-5-ANDROSTEN-17-ONE, Adhesion G-protein coupled receptor G2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Guo, S.C, Xiao, P, Lin, H, Sun, J.P, Yu, X. | 登録日 | 2022-04-19 | 公開日 | 2022-08-10 | 最終更新日 | 2023-03-15 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structures of the ADGRG2-G s complex in apo and ligand-bound forms. Nat.Chem.Biol., 18, 2022
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7XKD
| Cryo-EM structure of DHEA-ADGRG2-BT-Gs complex | 分子名称: | 3-BETA-HYDROXY-5-ANDROSTEN-17-ONE, Adhesion G-protein coupled receptor G2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Guo, S.C, Xiao, P, Lin, H, Sun, J.P, Yu, X. | 登録日 | 2022-04-19 | 公開日 | 2022-08-10 | 最終更新日 | 2023-03-15 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structures of the ADGRG2-G s complex in apo and ligand-bound forms. Nat.Chem.Biol., 18, 2022
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7XK2
| Cryo-EM Structure of Human Niacin Receptor HCA2-Gi protein complex | 分子名称: | 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Yang, Y, Kang, H.J, Gao, R.G, Wang, J.J, Han, G.W, DiBerto, J.F, Wu, L.J, Tong, J.H, Qu, L, Wu, Y.R, Pileski, R, Li, X.M, Zhang, X.C, Zhao, S.W, Kenakin, T, Wang, Q, Stevens, R.C, Peng, W, Roth, B.L, Rao, Z.H, Liu, Z.J. | 登録日 | 2022-04-19 | 公開日 | 2023-02-22 | 最終更新日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into the human niacin receptor HCA2-G i signalling complex. Nat Commun, 14, 2023
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7XK8
| Cryo-EM structure of the Neuromedin U receptor 2 (NMUR2) in complex with G Protein and its endogeneous Peptide-Agonist NMU25 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Zhao, W, Wenru, Z, Mu, W, Minmin, L, Shutian, C, Tingting, T, Gisela, S, Holger, W, Albert, B, Cuiying, Y, Xiaojing, C, Han, S, Wu, B, Zhao, Q. | 登録日 | 2022-04-19 | 公開日 | 2023-02-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Ligand recognition and activation of neuromedin U receptor 2. Nat Commun, 13, 2022
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7XKI
| Human Cx36/GJD2 (N-terminal deletion BRIL-fused mutant) gap junction channel in soybean lipids (D6 symmetry) | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein,Soluble cytochrome b562 | 著者 | Cho, H.J, Lee, S.N, Jeong, H, Ryu, B, Lee, H.J, Woo, J.S, Lee, H.H. | 登録日 | 2022-04-19 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XKK
| Human Cx36/GJD2 gap junction channel in detergents | 分子名称: | Gap junction delta-2 protein | 著者 | Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. | 登録日 | 2022-04-19 | 公開日 | 2023-04-26 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XKA
| Structure of human beta2 adrenergic receptor bound to constrained epinephrine | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Camelid Antibody Fragment, Endolysin,Beta-2 adrenergic receptor, ... | 著者 | Xu, X, Shonberg, J, Kaindl, J, Clark, M, Stobel, A, Maul, L, Mayer, D, Hubner, H, Venkatakrishnan, A, Dror, R, Kobilka, B.K, Sunahara, R, Liu, X, Gmeiner, P. | 登録日 | 2022-04-19 | 公開日 | 2023-04-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Constrained catecholamines gain beta 2 AR selectivity through allosteric effects on pocket dynamics. Nat Commun, 14, 2023
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7XK9
| Structure of human beta2 adrenergic receptor bound to constrained isoproterenol | 分子名称: | (5R,6R)-6-(propan-2-ylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Camelid Antibody Fragment, Endolysin,Beta-2 adrenergic receptor, ... | 著者 | Xu, X, Shonberg, J, Kaindl, J, Clark, M, Stobel, A, Maul, L, Mayer, D, Hubner, H, Venkatakrishnan, A, Dror, R, Kobilka, B.K, Sunahara, R, Liu, X, Gmeiner, P. | 登録日 | 2022-04-19 | 公開日 | 2023-04-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Constrained catecholamines gain beta 2 AR selectivity through allosteric effects on pocket dynamics. Nat Commun, 14, 2023
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