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PDB: 1 results

7ZMZ
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BU of 7zmz by Molmil
Engineered Interleukin 2 bound to CD25 receptor
Descriptor: Interleukin-2, Interleukin-2 receptor subunit alpha
Authors:Fyfe, P.K, Moraga, I, Gaggero, S, Mitra, S.
Deposit date:2022-04-20
Release date:2022-12-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein.
Sci Immunol, 7, 2022

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