7XKE

Cryo-EM structure of DHEA-ADGRG2-FL-Gs complex

Summary for 7XKE

• Entry DOI: 10.2210/pdb7xke/pdb
• EMDB information: 33249
• Descriptor: mini-Gs, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: adgrg2, gpcr, membrane protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 5
• Total formula weight: 200852.62

Authors

Guo, S.C.,Xiao, P.,Lin, H.,Sun, J.P.,Yu, X. (deposition date: 2022-04-19, release date: 2022-08-10, Last modification date: 2023-03-15)

• Primary citation: Lin, H.,Xiao, P.,Bu, R.Q.,Guo, S.,Yang, Z.,Yuan, D.,Zhu, Z.L.,Zhang, C.X.,He, Q.T.,Zhang, C.,Ping, Y.Q.,Zhao, R.J.,Ma, C.S.,Liu, C.H.,Zhang, X.N.,Jiang, D.,Huang, S.,Xi, Y.T.,Zhang, D.L.,Xue, C.Y.,Yang, B.S.,Li, J.Y.,Lin, H.C.,Zeng, X.H.,Zhao, H.,Xu, W.M.,Yi, F.,Liu, Z.,Sun, J.P.,Yu, X.; Structures of the ADGRG2-G s complex in apo and ligand-bound forms.; Nat.Chem.Biol., 18:1196-1203, 2022; PubMed: 35982227; DOI: 10.1038/s41589-022-01084-6

Experimental method

ELECTRON MICROSCOPY (2.9 Å)