PDB: 5425 件ウェブページステータス検索Chemie searchBIRD

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7Z8A	Sam68 分子名称: 1,2-ETHANEDIOL, KHDR1 protein, LITHIUM ION, ... 著者 Nadal, M, Fuentes-Prior, P. 登録日 2022-03-16 公開日 2023-02-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts. Protein Sci., 32, 2023
7ZAC	Sam68 分子名称: 1,2-ETHANEDIOL, KHDR1 protein, NITRATE ION 著者 Nadal, M, Fuentes-Prior, P. 登録日 2022-03-22 公開日 2023-02-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts. Protein Sci., 32, 2023
7ZAF	Sam68 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... 著者 Nadal, M, Puestes-Prior, P. 登録日 2022-03-22 公開日 2023-02-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts. Protein Sci., 32, 2023
6EHT	Modulation of PCNA sliding surface by p15PAF suggests a suppressive mechanism for cisplatin-induced DNA lesion bypass by pol eta holoenzyme 分子名称: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), PCNA-associated factor, ... 著者 De March, M, Barrera-Vilarmau, S, Mentegari, E, Merino, N, Bressan, E, Maga, G, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A. 登録日 2017-09-15 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 p15PAF binding to PCNA modulates the DNA sliding surface. Nucleic Acids Res., 46, 2018
6ERG	Complex of XLF and heterodimer Ku bound to DNA 分子名称: DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ... 著者 Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. 登録日 2017-10-18 公開日 2018-10-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining. Nat. Struct. Mol. Biol., 25, 2018
8HR1	Cryo-EM structure of SSX1 bound to the unmodified nucleosome at a resolution of 3.02 angstrom 分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... 著者 Zebin, T, Ai, H.S, Ziyu, X, Man, P, Liu, L. 登録日 2022-12-14 公開日 2023-09-13 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.02 Å) 主引用文献 Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes. Nat.Struct.Mol.Biol., 31, 2024
6ERH	Complex of XLF and heterodimer Ku bound to DNA 分子名称: DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ... 著者 Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. 登録日 2017-10-18 公開日 2018-10-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining. Nat. Struct. Mol. Biol., 25, 2018
8H0J	Annexin A5 mutant 分子名称: Annexin A5, CALCIUM ION 著者 Hua, Z.C, Tang, W. 登録日 2022-09-29 公開日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 structure dissection of the membrane aggregation mechanism induced by Annexin A5 mutation To Be Published
6EOF	Crystal structure of AMPylated GRP78 in ADP state 分子名称: 78 kDa glucose-regulated protein, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Yan, Y, Preissler, S, Read, R.J, Ron, D. 登録日 2017-10-09 公開日 2017-11-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation. Elife, 6, 2017
8HLW	Crystal structure of SIRT3 in complex with H4K16la peptide 分子名称: (2S)-2-HYDROXYPROPANOIC ACID, Histone H4 residues 20-27, NAD-dependent protein deacetylase sirtuin-3, ... 著者 Zhuming, F, Hao, Q. 登録日 2022-12-01 公開日 2023-09-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Identification of SIRT3 as an eraser of H4K16la. Iscience, 26, 2023
8HQY	Cryo-EM structure of SSX1 bound to the H2AK119Ub nucleosome at a resolution of 3.05 angstrom 分子名称: DNA (136-MER), DNA (137-MER), Histone H2A type 1-B/E, ... 著者 Zebin, T, Ai, H.S, Ziyu, X, GuoChao, C, Man, P, Liu, L. 登録日 2022-12-14 公開日 2023-09-27 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes. Nat.Struct.Mol.Biol., 31, 2024
6EIH	The crystal structure of 14-3-3 epsilon in complex with the phosphorylated NELFE peptide 分子名称: 14-3-3 protein epsilon, SER-ILE-SEP-ARG 著者 Akutsu, M, Wagner, S.A, Beli, P. 登録日 2017-09-19 公開日 2018-02-14 最終更新日 2019-10-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage. Nat Commun, 9, 2018
8H3H	Human ATAD2 Walker B mutant, ATP state 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase family AAA domain-containing protein 2 著者 Cho, C, Song, J. 登録日 2022-10-08 公開日 2023-10-18 実験手法 ELECTRON MICROSCOPY (3.15 Å) 主引用文献 Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication. Commun Biol, 6, 2023
8HQ6	KL2 in complex with CRM1-Ran-RanBP1 分子名称: CHLORIDE ION, CRM1 isoform 1, DIMETHYL SULFOXIDE, ... 著者 Sun, Q, Jian, L. 登録日 2022-12-13 公開日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Discovery of Aminoratjadone Derivatives as Potent Noncovalent CRM1 Inhibitors. J.Med.Chem., 66, 2023
8HQ3	KL1 in complex with CRM1-Ran-RanBP1 分子名称: CHLORIDE ION, CRM1 isoform 1, DIMETHYL SULFOXIDE, ... 著者 Sun, Q, Jian, L. 登録日 2022-12-13 公開日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of Aminoratjadone Derivatives as Potent Noncovalent CRM1 Inhibitors. J.Med.Chem., 66, 2023
6ERF	Complex of APLF factor and Ku heterodimer bound to DNA 分子名称: Aprataxin and PNK-like factor, DNA (34-MER), DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), ... 著者 Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. 登録日 2017-10-18 公開日 2018-10-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining. Nat.Struct.Mol.Biol., 25, 2018
7YPZ	Zafirlukast in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... 著者 Sun, Q, Lei, Y. 登録日 2022-08-05 公開日 2023-08-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Searching for Novel Noncovalent Nuclear Export Inhibitors through a Drug Repurposing Approach. J.Med.Chem., 66, 2023
7ZAU	Fascin-1 in complex with Nb 3E11 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fascin, ... 著者 Burgess, S.G, Bayliss, R. 登録日 2022-03-22 公開日 2023-09-27 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A nanobody inhibitor of Fascin-1 actin-bundling activity and filopodia formation. Open Biology, 14, 2024
8H9Z	Annexin A5 protein mutant 分子名称: Annexin A5, CALCIUM ION 著者 Hua, Z.C, Tang, W. 登録日 2022-10-26 公開日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 structure dissection of the membrane aggregation mechanism induced by Annexin A5 mutation To Be Published
8HE7	ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor 分子名称: 1-[[4-fluoranyl-3-(3-oxidanylidene-4-pentan-3-yl-piperazin-1-yl)carbonyl-phenyl]methyl]quinazoline-2,4-dione, Poly [ADP-ribose] polymerase 1, processed C-terminus, ... 著者 Wang, X.Y, Zhou, J, Xu, B.L. 登録日 2022-11-07 公開日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of Quinazoline-2,4(1 H ,3 H )-dione Derivatives Containing a Piperizinone Moiety as Potent PARP-1/2 Inhibitors─Design, Synthesis, In Vivo Antitumor Activity, and X-ray Crystal Structure Analysis. J.Med.Chem., 66, 2023
8HQ4	B27 in complex with CRM1-Ran-RanBP1 分子名称: 3-[(4-fluorophenyl)carbonylamino]-4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]benzoic acid, CHLORIDE ION, CRM1 isoform 1, ... 著者 Lei, Y, Sun, Q. 登録日 2022-12-13 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 B27 in complex with CRM1-Ran-RanBP1 To Be Published
6FCB	Human Methionine Adenosyltransferase II mutant (P115G) 分子名称: (DIPHOSPHONO)AMINOPHOSPHONIC ACID, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Panmanee, J, Antonyuk, S.V, Hasnain, S.S. 登録日 2017-12-20 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Control and regulation of S-Adenosylmethionine biosynthesis by the regulatory beta subunit and quinolone-based compounds. Febs J., 286, 2019
7ZVX	Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 2.4 A resolution 分子名称: 1,2-ETHANEDIOL, 2'-methoxyethyl DNA gapmer antisense oligonucleotide, Annexin A2, ... 著者 Hyjek-Skladanowska, M, Anderson, B, Mykhaylyk, V, Orr, C, Wagner, A, Skowronek, K, Seth, P, Nowotny, M. 登録日 2022-05-17 公開日 2022-09-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding. Nucleic Acids Res., 51, 2023
7ZVN	Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 1.87 A resolution 分子名称: 2'-methoxyethyl DNA gapmer antisense oligonucleotide, Annexin A2, CALCIUM ION, ... 著者 Hyjek-Skladanowska, M, Anderson, B, Mykhaylyk, V, Orr, C, Wagner, A, Skowronek, K, Seth, P, Nowotny, M. 登録日 2022-05-16 公開日 2022-09-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding. Nucleic Acids Res., 51, 2023
8HQ5	G6 in complex with CRM1-Ran-RanBP1 分子名称: 3-[(4-bromophenyl)carbonylamino]-4-[4-(5-chloranyl-2-methyl-phenyl)piperazin-1-yl]benzoic acid, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... 著者 Sun, Q, Lei, Y. 登録日 2022-12-13 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 F1 in complex with CRM1-Ran-RanBP1 To Be Published

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