8HLW

Crystal structure of SIRT3 in complex with H4K16la peptide

Summary for 8HLW

Entry DOI	10.2210/pdb8hlw/pdb
Descriptor	NAD-dependent protein deacetylase sirtuin-3, mitochondrial, Histone H4 residues 20-27, ZINC ION, ... (5 entities in total)
Functional Keywords	sirt3, lysine lactylation eraser, hydrolase
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	32322.59
Authors	Zhuming, F.,Hao, Q. (deposition date: 2022-12-01, release date: 2023-09-27, Last modification date: 2023-11-15)
Primary citation	Fan, Z.,Liu, Z.,Zhang, N.,Wei, W.,Cheng, K.,Sun, H.,Hao, Q. Identification of SIRT3 as an eraser of H4K16la. Iscience, 26:107757-107757, 2023 Cited by PubMed: 37720100 DOI: 10.1016/j.isci.2023.107757 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation