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5T9G
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BU of 5t9g by Molmil
Crystal structure of BuGH2Cwt in complex with Galactoisofagomine
分子名称: 1,2-ETHANEDIOL, D-galacto-isofagomine, Glycoside Hydrolase
著者Pluvinage, B, Boraston, A.B.
登録日2016-09-09
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont.
Nat Commun, 9, 2018
5TA7
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BU of 5ta7 by Molmil
Crystal structure of BuGH117Bwt
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycoside Hydrolase, ...
著者Pluvinage, B, Boraston, A.B.
登録日2016-09-09
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont.
Nat Commun, 9, 2018
5TA0
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BU of 5ta0 by Molmil
Crystal structure of BuGH86E322Q in complex with neoagarooctaose
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ...
著者Pluvinage, B, Boraston, A.B, Abbott, W.D.
登録日2016-09-09
公開日2017-09-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont.
Nat Commun, 9, 2018
6SU5
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BU of 6su5 by Molmil
Ph2119 endolysin from Thermus scotoductus MAT2119 bacteriophage Ph2119
分子名称: GLYCEROL, Lysozyme, PHOSPHATE ION, ...
著者Hakansson, M, Al-Karadaghi, S, Plotka, M, Kaczorowska, A.K, Kaczorowski, T.
登録日2019-09-13
公開日2020-09-30
最終更新日2021-04-14
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Molecular Characterization of a Novel Lytic Enzyme LysC from Clostridium intestinale URNW and Its Antibacterial Activity Mediated by Positively Charged N -Terminal Extension.
Int J Mol Sci, 21, 2020
6TRO
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BU of 6tro by Molmil
Crystal structure of the T-cell receptor GVY01 bound to HLA A2*01-GVYDGREHTV
分子名称: Beta-2-microglobulin, MAGE-A4 peptide (amino acids 230-239), MHC class I antigen, ...
著者Coles, C.H, McMurran, C, Lloyd, A, Hibbert, L, Lupardus, P.J, Cole, D.K, Harper, S.
登録日2019-12-19
公開日2020-06-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4.
J.Biol.Chem., 295, 2020
6TRN
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BU of 6trn by Molmil
Crystal structure of HLA A2*01-AVYDGREHTV
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, MAGE-A4 peptide (amino acids 230-239) variant, ...
著者Coles, C.H, McMurran, C, Lloyd, A, Hibbert, L, Lupardus, P.J, Cole, D.K, Harper, S.
登録日2019-12-19
公開日2020-06-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4.
J.Biol.Chem., 295, 2020
7KHJ
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BU of 7khj by Molmil
Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX8512 in the DFG-in state
分子名称: 2-phenyl-5-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine, Mast/stem cell growth factor receptor Kit
著者Zhang, Y.
登録日2020-10-21
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial.
Jama Oncol, 7, 2021
7KHK
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BU of 7khk by Molmil
Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX9486 (bezuclastinib) in the DFG-in state
分子名称: 4,5-dimethyl-N-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazole-3-carboxamide, Mast/stem cell growth factor receptor Kit
著者Zhang, Y.
登録日2020-10-21
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial.
Jama Oncol, 7, 2021
7KHG
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BU of 7khg by Molmil
Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX3397
分子名称: 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine, Mast/stem cell growth factor receptor Kit
著者Zhang, Y.
登録日2020-10-21
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial.
Jama Oncol, 7, 2021
5IRF
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BU of 5irf by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P1 space group
分子名称: POTASSIUM ION, Retron-type reverse transcriptase
著者Zhao, C, Pyle, A.M.
登録日2016-03-13
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
6H16
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BU of 6h16 by Molmil
Structure of LRP6 P3E3P4E4 in complex with VHH L-P2-D07
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Low-density lipoprotein receptor-related protein 6, ...
著者Gros, P, van Scherpenzeel, R.C.
登録日2018-07-11
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.
Nat Commun, 10, 2019
6CZR
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BU of 6czr by Molmil
The structure of amicetin bound to the 70S ribosome
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Eiler, D.R, Steitz, T.A, Looper, R.E, Serrano, C.M, Kannareddy, H.R, Koch, M.R, Barrows, L.R, Testa, C.A, Sebahar, P.R.
登録日2018-04-09
公開日2019-04-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Unifying the Aminohexopyranose- and Peptidyl-Nucleoside Antibiotics: Implications for Antibiotic Design
Angew.Chem.Int.Ed.Engl., 132, 2020
5IRG
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BU of 5irg by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P212121 space group
分子名称: POTASSIUM ION, Retron-type reverse transcriptase
著者Zhao, C, Pyle, A.M.
登録日2016-03-13
公開日2016-05-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
6H15
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BU of 6h15 by Molmil
Structure of LRP6 P3E3P4E4 in complex with VHH L-P2-B10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Gros, P, van Scherpenzeel, R.C.
登録日2018-07-11
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.
Nat Commun, 10, 2019
4XKM
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BU of 4xkm by Molmil
Crystal structure of Xylose Isomerase from an human intestinal tract microbe Bacteroides thetaiotaomicron
分子名称: MANGANESE (II) ION, Xylose isomerase
著者Han, B.G, Bong, S.M, Cho, J.W, Lee, B.I.
登録日2015-01-12
公開日2015-12-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of a class 2 D-xylose isomerase from the human intestinal tract microbe Bacteroides thetaiotaomicron
Biodesign, 3, 2015
6DRR
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BU of 6drr by Molmil
Crystal structure of Cj0485 dehydrogenase
分子名称: 1,2-ETHANEDIOL, Short-chain dehydrogenase
著者Pluvinage, B, Boraston, A.B.
登録日2018-06-12
公開日2019-07-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献The gastrointestinal pathogen Campylobacter jejuni metabolizes sugars with potential help from commensal Bacteroides vulgatus.
Commun Biol, 3, 2020
6DS1
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BU of 6ds1 by Molmil
Crystal structure of Cj0485 dehydrogenase in complex with NADP+
分子名称: GLYCEROL, MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Pluvinage, B, Boraston, A.B.
登録日2018-06-13
公開日2019-07-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.119 Å)
主引用文献The gastrointestinal pathogen Campylobacter jejuni metabolizes sugars with potential help from commensal Bacteroides vulgatus.
Commun Biol, 3, 2020
3IB2
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BU of 3ib2 by Molmil
structure of the complex of C-terminal half (C-lobe) of bovine lactoferrin with alpha-methyl-4-(2-methylpropyl) benzene acetic acid
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
著者Mir, R, Vikram, G, Kumar, R.P, Sinha, M, Singh, N, Sharma, S, Kaur, P, Singh, T.P.
登録日2009-07-15
公開日2009-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献The structural basis for the prevention of nonsteroidal antiinflammatory drug-induced gastrointestinal tract damage by the C-lobe of bovine colostrum lactoferrin.
Biophys.J., 97, 2009
1N5Q
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BU of 1n5q by Molmil
Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with dehydrated Sancycline
分子名称: 4-DIMETHYLAMINO-1,10,11,12-TETRAHYDROXY-3-OXO-3,4,4A,5-TETRAHYDRO-NAPHTHACENE-2-CARBOXYLIC ACID AMIDE, ActaVA-Orf6 monooxygenase, HEXAETHYLENE GLYCOL
著者Sciara, G, Kendrew, S.G, Miele, A.E, Marsh, N.G, Federici, L, Malatesta, F, Schimperna, G, Savino, C, Vallone, B.
登録日2002-11-07
公開日2003-01-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22, 2003
1N5S
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BU of 1n5s by Molmil
Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with the ligand Acetyl Dithranol
分子名称: (1,8-DIHYDROXY-9-OXO-9,10-DIHYDRO-ANTHRACEN-2-YL)-ACETIC ACID, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ActVA-Orf6 monooxygenase
著者Sciara, G, Kendrew, S.G, Miele, A.E, Marsh, N.G, Federici, L, Malatesta, F, Schimperna, G, Savino, C, Vallone, B.
登録日2002-11-07
公開日2003-01-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22, 2003
1N5T
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BU of 1n5t by Molmil
Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with the ligand Oxidized Acetyl Dithranol
分子名称: (1,8-DIHYDROXY-9,10-DIOXO-9,10-DIHYDRO-ANTHRACEN-2-YL)-ACETIC ACID, ActVA-Orf6 monooxygenase
著者Sciara, G, G Kendrew, S, Miele, A.E, Marsh, N.G, Federici, L, Malatesta, F, Schimperna, G, Savino, C, Vallone, B.
登録日2002-11-07
公開日2003-01-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22, 2003
1N5V
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BU of 1n5v by Molmil
Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with the ligand Nanaomycin D
分子名称: 7-HYDROXY-5-METHYL-3,3A,5,11B-TETRAHYDRO-1,4-DIOXA-CYCLOPENTA[A]ANTHRACENE-2,6,11-TRIONE, ActVA-Orf6 monooxygenase
著者Sciara, G, Kendrew, S.G, Miele, A.E, Marsh, N.G, Federici, L, Malatesta, F, Schimperna, G, Savino, C, Vallone, B.
登録日2002-11-07
公開日2003-01-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22, 2003
5IT2
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BU of 5it2 by Molmil
Structure of a transglutaminase 2-specific autoantibody 693-10-B06 Fab fragment
分子名称: heavy chain, light chain
著者Chen, X, Dalhus, B, Hnida, K, Iversen, R, Sollid, L.M.
登録日2016-03-16
公開日2017-03-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions
Nat. Med., 18, 2012
1ETN
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BU of 1etn by Molmil
MOLECULAR STRUCTURE OF THE TOXIC DOMAIN OF HEAT-STABLE ENTEROTOXIN PRODUCED BY A PATHOGENIC STRAIN OF ESCHERICHIA COLI
分子名称: 5-BETA-MERCAPTOPROPIONATE HEAT-STABLE ENTEROTOXIN
著者Sato, T, Shimonishi, Y.
登録日1994-03-15
公開日1996-01-29
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (0.89 Å)
主引用文献Molecular structure of the toxin domain of heat-stable enterotoxin produced by a pathogenic strain of Escherichia coli. A putative binding site for a binding protein on rat intestinal epithelial cell membranes.
J.Biol.Chem., 266, 1991
5UJ6
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Crystal Structure of Bacteroides Uniformis beta-glucuronidase
分子名称: CALCIUM ION, GLYCEROL, Glycosyl hydrolases family 2, ...
著者Walton, W.G, Redinbo, M.R.
登録日2017-01-17
公開日2017-06-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An Atlas of beta-Glucuronidases in the Human Intestinal Microbiome.
Structure, 25, 2017

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