1N5V

Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with the ligand Nanaomycin D

Summary for 1N5V

Related1LQ9 1N5Q 1N5S 1N5T
DescriptorActVA-Orf6 monooxygenase, 7-HYDROXY-5-METHYL-3,3A,5,11B-TETRAHYDRO-1,4-DIOXA-CYCLOPENTA[A]ANTHRACENE-2,6,11-TRIONE (3 entities in total)
Functional Keywordsmonooxygenase, aromatic polyketides, actinorhodin, dihydrokalafungin, nanaomycin d, streptomyces coelicolor, oxidoreductase
Biological sourceStreptomyces coelicolor
Total number of polymer chains2
Total molecular weight24257.1
Authors
Sciara, G.,Kendrew, S.G.,Miele, A.E.,Marsh, N.G.,Federici, L.,Malatesta, F.,Schimperna, G.,Savino, C.,Vallone, B. (deposition date: 2002-11-07, release date: 2003-01-14, Last modification date: 2011-07-13)
Primary citation
Sciara, G.,Kendrew, S.G.,Miele, A.E.,Marsh, N.G.,Federici, L.,Malatesta, F.,Schimperna, G.,Savino, C.,Vallone, B.
The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22:205-215, 2003
PubMed: 12514126 (PDB entries with the same primary citation)
DOI: 10.1093/emboj/cdg031
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.24 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2491004.0%4.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1n5v
no rotation
Molmil generated image of 1n5v
rotated about x axis by 90°
Molmil generated image of 1n5v
rotated about y axis by 90°