Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with the ligand Oxidized Acetyl Dithranol

Summary for 1N5T

Related1LQ9 1N5Q 1N5S 1N5V
DescriptorActVA-Orf6 monooxygenase, (1,8-DIHYDROXY-9,10-DIOXO-9,10-DIHYDRO-ANTHRACEN-2-YL)-ACETIC ACID (3 entities in total)
Functional Keywordsmonooxygenase, aromatic polyketides, actinorhodin, dihydrokalafungin, oxidized acetyl dithranol, streptomyces coelicolor, oxidoreductase
Biological sourceStreptomyces coelicolor
Total number of polymer chains2
Total molecular weight24255.09
Sciara, G.,G Kendrew, S.,Miele, A.E.,Marsh, N.G.,Federici, L.,Malatesta, F.,Schimperna, G.,Savino, C.,Vallone, B. (deposition date: 2002-11-07, release date: 2003-01-14, Last modification date: 2011-07-13)
Primary citation
Sciara, G.,Kendrew, S.G.,Miele, A.E.,Marsh, N.G.,Federici, L.,Malatesta, F.,Schimperna, G.,Savino, C.,Vallone, B.
The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22:205-215, 2003
PubMed: 12514126 (PDB entries with the same primary citation)
DOI: 10.1093/emboj/cdg031
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers50.5%1.1%3.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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