1N5Q

Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with dehydrated Sancycline

Summary for 1N5Q

Related1LQ9 1N5S 1N5T 1N5V
DescriptorActaVA-Orf6 monooxygenase, HEXAETHYLENE GLYCOL, 4-DIMETHYLAMINO-1,10,11,12-TETRAHYDROXY-3-OXO-3,4,4A,5-TETRAHYDRO-NAPHTHACENE-2-CARBOXYLIC ACID AMIDE, ... (4 entities in total)
Functional Keywordsmonooxygenase, aromatic polyketides, actinorhodin, dihydrokalafungin, sancycline, streptomyces coelicolor, oxidoreductase
Biological sourceStreptomyces coelicolor
Total number of polymer chains2
Total molecular weight24635.56
Authors
Sciara, G.,Kendrew, S.G.,Miele, A.E.,Marsh, N.G.,Federici, L.,Malatesta, F.,Schimperna, G.,Savino, C.,Vallone, B. (deposition date: 2002-11-07, release date: 2003-01-14, Last modification date: 2011-07-13)
Primary citation
Sciara, G.,Kendrew, S.G.,Miele, A.E.,Marsh, N.G.,Federici, L.,Malatesta, F.,Schimperna, G.,Savino, C.,Vallone, B.
The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22:205-215, 2003
PubMed: 12514126 (PDB entries with the same primary citation)
DOI: 10.1093/emboj/cdg031
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.74 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers1203.4%3.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution