3IB2

structure of the complex of C-terminal half (C-lobe) of bovine lactoferrin with alpha-methyl-4-(2-methylpropyl) benzene acetic acid

Replaces:  3HWQReplaces:  2QZ1Replaces:  3FKX

Summary for 3IB2

• Entry DOI: 10.2210/pdb3ib2/pdb
• Related: 2DWA 2DXY 2O51
• Descriptor: Lactotransferrin, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: complex, ibuprofen, c-lobe, metal binding protein, antibiotic, antimicrobial, disulfide bond, glycoprotein, hydrolase, ion transport, iron, iron transport, metal-binding, phosphoprotein, protease, secreted, serine protease, transport
• Biological source: Bos taurus (Bovine)
• Total number of polymer chains: 1
• Total formula weight: 39639.86

Authors

Mir, R.,Vikram, G.,Kumar, R.P.,Sinha, M.,Singh, N.,Sharma, S.,Kaur, P.,Singh, T.P. (deposition date: 2009-07-15, release date: 2009-07-28, Last modification date: 2023-11-01)

• Primary citation: Mir, R.,Singh, N.,Vikram, G.,Kumar, R.P.,Sinha, M.,Bhushan, A.,Kaur, P.,Srinivasan, A.,Sharma, S.,Singh, T.P.; The structural basis for the prevention of nonsteroidal antiinflammatory drug-induced gastrointestinal tract damage by the C-lobe of bovine colostrum lactoferrin.; Biophys.J., 97:3178-3186, 2009; PubMed: 20006955; DOI: 10.1016/j.bpj.2009.09.030

Experimental method

X-RAY DIFFRACTION (2.29 Å)