5IT2
Structure of a transglutaminase 2-specific autoantibody 693-10-B06 Fab fragment
Summary for 5IT2
Entry DOI | 10.2210/pdb5it2/pdb |
Descriptor | heavy chain, light chain (3 entities in total) |
Functional Keywords | transglutaminase 2, autoantibody, fab fragment, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 47889.53 |
Authors | Chen, X.,Dalhus, B.,Hnida, K.,Iversen, R.,Sollid, L.M. (deposition date: 2016-03-16, release date: 2017-03-22, Last modification date: 2023-11-08) |
Primary citation | Di Niro, R.,Mesin, L.,Zheng, N.Y.,Stamnaes, J.,Morrissey, M.,Lee, J.H.,Huang, M.,Iversen, R.,du Pre, M.F.,Qiao, S.W.,Lundin, K.E.,Wilson, P.C.,Sollid, L.M. High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions Nat. Med., 18:441-445, 2012 Cited by PubMed: 22366952DOI: 10.1038/nm.2656 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report