PDB: 467 件ウェブページステータス検索Chemie searchBIRD

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6ZFA	Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcIFG, alpha-1,2-mannobiose and hexatungstotellurate(VI) TEW 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, 6-tungstotellurate(VI), ... 著者 Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. 登録日 2020-06-16 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
6FF3	Crystal structure of Drosophila neural ectodermal development factor Imp-L1 with Human IGF-I 分子名称: Insulin-like growth factor I, Neural/ectodermal development factor IMP-L2 著者 Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D, Viola, C.M. 登録日 2018-01-03 公開日 2018-09-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones. Nat Commun, 9, 2018
6ZFN	Structure of an inactive E404Q variant of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with 1-methyl alpha-1,2-mannobiose 分子名称: Glycoprotein endo-alpha-1,2-mannosidase, SULFATE ION, alpha-D-mannopyranose-(1-2)-methyl alpha-D-mannopyranoside 著者 Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. 登録日 2020-06-17 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
4E7A	Crystal structure of a product state assembly of HCV NS5B genotype 2a JFH-1 isolate with beta hairpin deletion bound to primer-template RNA with a 2',3'-ddC 分子名称: 5'-R(*CP*AP*UP*GP*GP*C)-D(P*(DOC))-3', RNA-directed RNA polymerase 著者 Edwards, T.E, Mosley, R.T. 登録日 2012-03-16 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of hepatitis C virus polymerase in complex with primer-template RNA. J.Virol., 86, 2012
4E76	Apo crystal structure of HCV NS5B genotype 2A JFH-1 isolate with beta hairpin loop deletion 分子名称: 1,2-ETHANEDIOL, RNA-directed RNA polymerase, SULFATE ION 著者 Edwards, T.E, Mosley, R.T. 登録日 2012-03-16 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of hepatitis C virus polymerase in complex with primer-template RNA. J.Virol., 86, 2012
4E78	Crystal structure of a product state assembly of HCV NS5B genotype 2a JFH-1 isolate with beta hairpin loop deletion bound to primer-template RNA with 3'-dG 分子名称: 5'-R(*U*AP*CP*CP*GP*(GDO))-3', PROTEIN (RNA-directed RNA polymerase) 著者 Edwards, T.E, Mosley, R.T. 登録日 2012-03-16 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of hepatitis C virus polymerase in complex with primer-template RNA. J.Virol., 86, 2012
8CQH	Ntaya virus methyltransferase in complex with GTP and SAH 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein, MAGNESIUM ION, ... 著者 Boura, E, Krejcova, K. 登録日 2023-03-06 公開日 2024-03-13 最終更新日 2024-09-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and functional insights in flavivirus NS5 proteins gained by the structure of Ntaya virus polymerase and methyltransferase. Structure, 32, 2024
2GG1	NMR solution structure of domain III of the E-protein of tick-borne Langat flavivirus (includes RDC restraints) 分子名称: Genome polyprotein 著者 Mukherjee, M, Dutta, K, White, M.A, Cowburn, D, Fox, R.O. 登録日 2006-03-23 公開日 2006-04-25 最終更新日 2023-11-29 実験手法 SOLUTION NMR 主引用文献 NMR solution structure and backbone dynamics of domain III of the E protein of tick-borne Langat flavivirus suggests a potential site for molecular recognition. Protein Sci., 15, 2006
8EF3	Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ119-D 分子名称: rhMZ119-D antibody heavy chain, rhMZ119-D antibody light chain 著者 Sankhala, R.S, Joyce, M.G. 登録日 2022-09-07 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.672 Å) 主引用文献 Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023
8EE8	Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ100-C in complex with ZIKV E glycoprotein 分子名称: Envelope protein E, rhMZ100-C antibody heavy chain, rhMZ100-C antibody light chain 著者 Sankhala, R.S, Joyce, M.G. 登録日 2022-09-06 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.803 Å) 主引用文献 Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023
8EE5	Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ119-D in complex with ZIKV E glycoprotein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, rhMZ119-D antibody heavy chain, ... 著者 Sankhala, R.S, Joyce, M.G. 登録日 2022-09-06 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.583 Å) 主引用文献 Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023
8EED	Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ107-B in complex with ZIKV E glycoprotein 分子名称: Envelope protein E, rhMZ107-B antibody heavy chain, rhMZ107-B antibody light chain 著者 Sankhala, R.S, Joyce, M.G. 登録日 2022-09-07 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.487 Å) 主引用文献 Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023
8EF0	Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ104-D 分子名称: PHOSPHATE ION, ZINC ION, rhMZ104-D antibody heavy chain, ... 著者 Sankhala, R.S, Joyce, M.G. 登録日 2022-09-07 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023
8EEE	Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ104-d in complex with ZIKV E glycoprotein 分子名称: Envelope protein E, SULFATE ION, rhMZ104-D antibody heavy chain, ... 著者 Sankhala, R.S, Joyce, M.G. 登録日 2022-09-07 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.819 Å) 主引用文献 Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023
8EF1	Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ103-A 分子名称: rhMZ103-A antibody heavy chain, rhMZ103-A antibody light chain 著者 Sankhala, R.S, Joyce, M.G. 登録日 2022-09-07 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023
8EEZ	Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ100-C 分子名称: rhMZ100-C antibody heavy chain, rhMZ100-C antibody light chain 著者 Sankhala, R.S, Joyce, M.G. 登録日 2022-09-07 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023
8EF2	Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ107-B 分子名称: PHOSPHATE ION, rhMZ107-B antibody heavy chain, rhMZ107-B antibody light chain 著者 Sankhala, R.S, Joyce, M.G. 登録日 2022-09-07 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023
4GUA	Alphavirus P23pro-zbd 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Non-structural polyprotein, SULFATE ION, ... 著者 Shin, G, Yost, S, Miller, M, Marcotrigiano, J. 登録日 2012-08-29 公開日 2012-10-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.854 Å) 主引用文献 Structural and functional insights into alphavirus polyprotein processing and pathogenesis. Proc.Natl.Acad.Sci.USA, 109, 2012
2GGV	Crystal structure of the West Nile virus NS2B-NS3 protease, His51Ala mutant 分子名称: non-structural protein 2B, non-structural protein 3 著者 Aleshin, A.E, Shiryaev, S.A, Strongin, A.Y, Liddington, R.C. 登録日 2006-03-24 公開日 2007-03-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold. Protein Sci., 16, 2007
2HCN	Crystal structure of RNA dependent RNA polymerase domain from west nile virus 分子名称: CALCIUM ION, RNA-directed RNA polymerase (NS5), ZINC ION 著者 Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP) 登録日 2006-06-17 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5 J.Biol.Chem., 282, 2007
2HCS	Crystal structure of RNA dependant RNA polymerase domain of West Nile virus 分子名称: RNA-directed RNA polymerase (NS5), ZINC ION 著者 Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP) 登録日 2006-06-18 公開日 2007-02-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5 J.Biol.Chem., 282, 2007
2HFZ	Crystal structure of RNA dependent RNA polymerase domain from West Nile virus 分子名称: MAGNESIUM ION, RNA-directed RNA polymerase(NS5), ZINC ION 著者 Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP) 登録日 2006-06-26 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5 J.Biol.Chem., 282, 2007
2HG0	Structure of the West Nile Virus envelope glycoprotein 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein 著者 Nybakken, G.E, Nelson, C.A, Chen, B.R, Diamond, M.S, Fremont, D.H. 登録日 2006-06-26 公開日 2006-11-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the West Nile virus envelope glycoprotein. J.Virol., 80, 2006
3K1E	Crystal structure of odorant binding protein 1 (AaegOBP1) from Aedes aegypti 分子名称: 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, CHLORIDE ION, MAGNESIUM ION, ... 著者 Leite, N.R, Krogh, R, Leal, W.S, Iulek, J, Oliva, G. 登録日 2009-09-27 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of an odorant-binding protein from the mosquito Aedes aegypti suggests a binding pocket covered by a pH-sensitive "Lid". Plos One, 4, 2009
8TQX	Crystal structure of the Zika virus stem-loop A (SLA) bottom stem 分子名称: GLYCEROL, MAGNESIUM ION, Zika virus stem-loop A (SLA) bottom stem 著者 Tipo, J, Gottipati, K, Choi, K.H. 登録日 2023-08-08 公開日 2024-03-06 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 High-resolution RNA tertiary structures in Zika virus stem-loop A for the development of inhibitory small molecules. Rna, 30, 2024

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