6FF3
Crystal structure of Drosophila neural ectodermal development factor Imp-L1 with Human IGF-I
Summary for 6FF3
Entry DOI | 10.2210/pdb6ff3/pdb |
Related | 1GZR 4CBP |
Descriptor | Neural/ectodermal development factor IMP-L2, Insulin-like growth factor I (3 entities in total) |
Functional Keywords | igf-i, insulin binding protein, drosophila, imaginal morphogenesis, peptide binding protein |
Biological source | Drosophila melanogaster (Fruit fly) More |
Total number of polymer chains | 2 |
Total formula weight | 34954.41 |
Authors | Brzozowski, A.M.,Kulahin, N.,Kristensen, O.,Schluckebier, G.,Meyts, P.D.,Viola, C.M. (deposition date: 2018-01-03, release date: 2018-09-26, Last modification date: 2024-01-17) |
Primary citation | Roed, N.K.,Viola, C.M.,Kristensen, O.,Schluckebier, G.,Norrman, M.,Sajid, W.,Wade, J.D.,Andersen, A.S.,Kristensen, C.,Ganderton, T.R.,Turkenburg, J.P.,De Meyts, P.,Brzozowski, A.M. Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones. Nat Commun, 9:3860-3860, 2018 Cited by PubMed: 30242155DOI: 10.1038/s41467-018-06192-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.57 Å) |
Structure validation
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