3K1E

Crystal structure of odorant binding protein 1 (AaegOBP1) from Aedes aegypti

Summary for 3K1E

• Entry DOI: 10.2210/pdb3k1e/pdb
• Descriptor: Odorant binding protein, MAGNESIUM ION, 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, ... (5 entities in total)
• Functional Keywords: insect odorant binding protein fold, odorant binding protein
• Biological source: Aedes aegypti (Yellowfever mosquito)
• Total number of polymer chains: 2
• Total formula weight: 30593.40

Authors

Leite, N.R.,Krogh, R.,Leal, W.S.,Iulek, J.,Oliva, G. (deposition date: 2009-09-27, release date: 2009-12-08, Last modification date: 2023-09-06)

Primary citation

Leite, N.R.,Krogh, R.,Xu, W.,Ishida, Y.,Iulek, J.,Leal, W.S.,Oliva, G.
Structure of an odorant-binding protein from the mosquito Aedes aegypti suggests a binding pocket covered by a pH-sensitive "Lid".
Plos One, 4:e8006-e8006, 2009

PubMed Abstract: The yellow fever mosquito, Aedes aegypti, is the primary vector for the viruses that cause yellow fever, mostly in tropical regions of Africa and in parts of South America, and human dengue, which infects 100 million people yearly in the tropics and subtropics. A better understanding of the structural biology of olfactory proteins may pave the way for the development of environmentally-friendly mosquito attractants and repellents, which may ultimately contribute to reduction of mosquito biting and disease transmission.

PubMed: 19956631
DOI: 10.1371/journal.pone.0008006

Experimental method

X-RAY DIFFRACTION (1.85 Å)