PDB: 5425 件ウェブページステータス検索Chemie searchBIRD

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7BED	X-ray structure of WDR5 bound to the WDR5 win motif peptide 分子名称: SULFATE ION, WD repeat-containing protein 5 著者 McVey, C.E, Kaye, K.M. 登録日 2020-12-23 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 MLL1 is regulated by KSHV LANA and is important for virus latency. Nucleic Acids Res., 49, 2021
7BCY	X-ray structure of WDR5delta24 bound to the Kaposi's sarcoma herpesvirus LANA win motif peptide 分子名称: ORF 73, WD repeat-containing protein 5 著者 McVey, C.E, Kaye, K.M. 登録日 2020-12-21 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 MLL1 is regulated by KSHV LANA and is important for virus latency. Nucleic Acids Res., 49, 2021
2KTU	Human eRF1 C-domain, "closed" conformer 分子名称: Eukaryotic peptide chain release factor subunit 1 著者 Mantsyzov, A.B, Polshakov, V.I, Birdsall, B. 登録日 2010-02-09 公開日 2010-06-09 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR assignments of the C-terminal domain of human polypeptide release factor eRF1. Biomol.Nmr Assign., 1, 2007
2KDP	Solution Structure of the SAP30 zinc finger motif 分子名称: Histone deacetylase complex subunit SAP30, ZINC ION 著者 He, Y, Imhoff, R, Sahu, A, Radhakrishnan, I. 登録日 2009-01-14 公開日 2009-03-17 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of a novel zinc finger motif in the SAP30 polypeptide of the Sin3 corepressor complex and its potential role in nucleic acid recognition Nucleic Acids Res., 37, 2009
4PJW	crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1), with bound MES 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog 著者 Hara, K, Chen, Z, Tomchick, D.R, Yu, H. 登録日 2014-05-12 公開日 2014-08-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion. Nat.Struct.Mol.Biol., 21, 2014
4PL7	Structure of Komagataella pastoris actin-thymosin beta4 hybrid 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin,Thymosin beta-4, CALCIUM ION 著者 Xue, B, Robinson, R.C. 登録日 2014-05-16 公開日 2014-10-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of thymosin-beta 4/profilin exchange leading to actin filament polymerization. Proc.Natl.Acad.Sci.USA, 111, 2014
4PJT	Structure of PARP1 catalytic domain bound to inhibitor BMN 673 分子名称: (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one, GLYCEROL, Poly [ADP-ribose] polymerase 1, ... 著者 Aoyagi-Scharber, M, Gardberg, A.S, Arakaki, T.L. 登録日 2014-05-12 公開日 2014-09-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural basis for the inhibition of poly(ADP-ribose) polymerases 1 and 2 by BMN 673, a potent inhibitor derived from dihydropyridophthalazinone. Acta Crystallogr.,Sect.F, 70, 2014
4PJU	crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1) 分子名称: Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog 著者 Hara, K, Chen, Z, Tomchick, D.R, Yu, H. 登録日 2014-05-12 公開日 2014-08-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion. Nat.Struct.Mol.Biol., 21, 2014
4PL8	Structure of rabbit skeletal muscle actin in complex with a hybrid peptide comprising thymosin beta4 and the lysine-rich region of Cordon-Bleu 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Xue, B, Robinson, R.C. 登録日 2014-05-16 公開日 2014-10-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of thymosin-beta 4/profilin exchange leading to actin filament polymerization. Proc.Natl.Acad.Sci.USA, 111, 2014
4PK7	crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1) with bound MES, native proteins 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog 著者 Hara, K, Chen, Z, Tomchick, D.R, Yu, H. 登録日 2014-05-13 公開日 2014-09-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion. Nat.Struct.Mol.Biol., 21, 2014
7EPZ	Overall structure of Erastin-bound xCT-4F2hc complex 分子名称: 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHATE, 2-[(1S)-1-[4-[2-(4-chloranylphenoxy)ethanoyl]piperazin-1-yl]ethyl]-3-(2-ethoxyphenyl)quinazolin-4-one, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Yan, R.H, Li, Y.N, Zhang, Y.Y, Chi, X.M, Zhou, Q. 登録日 2021-04-28 公開日 2022-04-06 最終更新日 2022-07-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis. Cell Res., 32, 2022
4RXQ	The structure of GTP-dUTP-bound SAMHD1 分子名称: DEOXYURIDINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Zhu, C.F, Wei, W, Peng, X, Dong, Y.H, Gong, Y, Yu, X.F. 登録日 2014-12-11 公開日 2015-03-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The mechanism of substrate-controlled allosteric regulation of SAMHD1 activated by GTP. Acta Crystallogr.,Sect.D, 71, 2015
4RXO	The structure of GTP-bound SAMHD1 分子名称: Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, ... 著者 Zhu, C.F, Wei, W, Peng, X, Dong, Y.H, Gong, Y, Yu, X.F. 登録日 2014-12-11 公開日 2015-03-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The mechanism of substrate-controlled allosteric regulation of SAMHD1 activated by GTP. Acta Crystallogr.,Sect.D, 71, 2015
7EQ7	Co-Crystal Structure Analysis of Annexin A2 and 5alpha-EAL 分子名称: Annexin A2, CALCIUM ION 著者 Liu, X, Yang, G. 登録日 2021-04-30 公開日 2022-05-11 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.111 Å) 主引用文献 Co-Crystal Structure Analysis of Annexin A2 and 5alpha-EAL To be published
4RV6	Human ARTD1 (PARP1) catalytic domain in complex with inhibitor Rucaparib 分子名称: Poly [ADP-ribose] polymerase 1, Rucaparib, SULFATE ION 著者 Karlberg, T, Thorsell, A.G, Schuler, H. 登録日 2014-11-25 公開日 2015-12-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors. J. Med. Chem., 60, 2017
2KIZ	Solution structure of Arkadia RING-H2 finger domain 分子名称: E3 ubiquitin-protein ligase Arkadia, ZINC ION 著者 Kandias, N.G, Chasapis, C.T, Bentrop, D, Episkopou, V, Spyroulias, G.A. 登録日 2009-05-13 公開日 2010-05-19 最終更新日 2013-03-20 実験手法 SOLUTION NMR 主引用文献 NMR-based insights into the conformational and interaction properties of Arkadia RING-H2 E3 Ub ligase. Proteins, 80, 2012
4TO0	Structure basis of cellular dNTP regulation, SAMHD1-GTP-dATP-dCTP complex 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... 著者 Ji, X, Tang, C, Zhao, Q, Wang, W, Xiong, Y. 登録日 2014-06-05 公開日 2014-10-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of cellular dNTP regulation by SAMHD1. Proc.Natl.Acad.Sci.USA, 111, 2014
4TO3	Structural basis of cellular dNTP regulation, SAMHD1-dGTP-dGTP-dCTP complex 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... 著者 Ji, X, Tang, C, Zhao, Q, Wang, W, Xiong, Y. 登録日 2014-06-05 公開日 2014-10-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis of cellular dNTP regulation by SAMHD1. Proc.Natl.Acad.Sci.USA, 111, 2014
2KMD	Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to co-activator CBP 分子名称: Protein C-ets-1 著者 Nelson, M.L, Kang, H, Lee, G.M, Blaszczak, A.G, Lau, D.K.W, McIntosh, L.P, Graves, B.J. 登録日 2009-07-27 公開日 2010-05-05 最終更新日 2012-03-21 実験手法 SOLUTION NMR 主引用文献 Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP. Proc.Natl.Acad.Sci.USA, 107, 2010
2KTV	Human eRF1 C-domain, "open" conformer 分子名称: Eukaryotic peptide chain release factor subunit 1 著者 Mantsyzov, A.B, Polshakov, V.I, Birdsall, B. 登録日 2010-02-09 公開日 2010-06-09 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor. Febs J., 277, 2010
7C2Z	Bromodomain-containing 4 BD1 in complex with 3',4',7,8-Tetrahydroxyflavone 分子名称: 2-[3,4-bis(oxidanyl)phenyl]-7,8-bis(oxidanyl)chromen-4-one, Bromodomain-containing protein 4, FORMIC ACID 著者 Li, J, Zhu, J. 登録日 2020-05-10 公開日 2021-05-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor. J Enzyme Inhib Med Chem, 36, 2021
2KTB	Solution Structure of the Second Bromodomain of Human Polybromo in complex with an acetylated peptide from Histone 3 分子名称: H3_Peptide, Protein polybromo-1 著者 Charlop-Powers, Z, Zhang, Q, Zeng, L. 登録日 2010-01-26 公開日 2010-05-12 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2. Cell Res., 20, 2010
2KNV	NMR dimer structure of the UBA domain of p62 (SQSTM1) 分子名称: Sequestosome-1 著者 Long, J.E, Searle, M.S. 登録日 2009-09-04 公開日 2009-12-15 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Dimerisation of the UBA Domain of p62 Inhibits Ubiquitin Binding and Regulates NF-kappaB Signalling J.Mol.Biol., 2009
4O78	Crystal structure of the first bromodomain of human BRD4 in complex with GW612286X 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, CHLORIDE ION, ... 著者 Zhu, J.-Y, Ember, S.W, Watts, C, Schonbrunn, E. 登録日 2013-12-24 公開日 2014-03-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Acetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase Inhibitors. Acs Chem.Biol., 9, 2014
2KRM	RDC refined solution structure of the first SH3 domain of CD2AP 分子名称: CD2-associated protein 著者 Ortega Roldan, J.A.J, Azuaga, A.I, van Nuland, N.A.J. 登録日 2009-12-21 公開日 2011-01-12 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution Structure, Dynamics and Thermodynamics of the three SH3 domains of CD2AP To be Published

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