7BCY

X-ray structure of WDR5delta24 bound to the Kaposi's sarcoma herpesvirus LANA win motif peptide

Summary for 7BCY

Entry DOI	10.2210/pdb7bcy/pdb
Descriptor	WD repeat-containing protein 5, ORF 73 (3 entities in total)
Functional Keywords	wd repeat-containing protein 5 lana histone methyltransferase h3k4, transcription, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	71673.39
Authors	McVey, C.E.,Kaye, K.M. (deposition date: 2020-12-21, release date: 2021-12-08, Last modification date: 2024-01-31)
Primary citation	Tan, M.,Li, S.,Juillard, F.,Chitas, R.,Custodio, T.F.,Xue, H.,Szymula, A.,Sun, Q.,Liu, B.,Alvarez, A.L.,Chen, S.,Huang, J.,Simas, J.P.,McVey, C.E.,Kaye, K.M. MLL1 is regulated by KSHV LANA and is important for virus latency. Nucleic Acids Res., 49:12895-12911, 2021 Cited by PubMed: 34850113 DOI: 10.1093/nar/gkab1094 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation