2KTB

Solution Structure of the Second Bromodomain of Human Polybromo in complex with an acetylated peptide from Histone 3

Summary for 2KTB

• Entry DOI: 10.2210/pdb2ktb/pdb
• NMR Information: BMRB: 16694
• Descriptor: H3_Peptide, Protein polybromo-1 (2 entities in total)
• Functional Keywords: bromodomain, alternative splicing, chromatin regulator, dna-binding, nucleus, phosphoprotein, transcription, transcription regulation, protein binding
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q86U86
• Total number of polymer chains: 2
• Total formula weight: 15908.33

Authors

Charlop-Powers, Z.,Zhang, Q.,Zeng, L. (deposition date: 2010-01-26, release date: 2010-05-12, Last modification date: 2023-11-15)

• Primary citation: Charlop-Powers, Z.,Zeng, L.,Zhang, Q.,Zhou, M.M.; Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2.; Cell Res., 20:529-538, 2010; PubMed: 20368734; DOI: 10.1038/cr.2010.43

Experimental method

SOLUTION NMR