2KMD
Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to co-activator CBP
Summary for 2KMD
| Entry DOI | 10.2210/pdb2kmd/pdb |
| Related | 2JV3 |
| NMR Information | BMRB: 16426 |
| Descriptor | Protein C-ets-1 (1 entity in total) |
| Functional Keywords | pnt domain, sam domain, ets-1, mapk phosphorylation, phosphoprotein, proto-oncogene, transcription, transcription regulation, protein binding, conformational dynamics |
| Biological source | Mus musculus (mouse) |
| Cellular location | Nucleus: P27577 |
| Total number of polymer chains | 1 |
| Total formula weight | 13009.75 |
| Authors | Nelson, M.L.,Kang, H.,Lee, G.M.,Blaszczak, A.G.,Lau, D.K.W.,McIntosh, L.P.,Graves, B.J. (deposition date: 2009-07-27, release date: 2010-05-05, Last modification date: 2012-03-21) |
| Primary citation | Nelson, M.L.,Kang, H.S.,Lee, G.M.,Blaszczak, A.G.,Lau, D.K.,McIntosh, L.P.,Graves, B.J. Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP. Proc.Natl.Acad.Sci.USA, 107:10026-10031, 2010 Cited by PubMed: 20534573DOI: 10.1073/pnas.0915137107 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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