PDB: 19040 件ウェブページステータス検索Chemie searchBIRD

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6QZP	High-resolution cryo-EM structure of the human 80S ribosome 分子名称: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S rRNA (1740-MER), 28S rRNA (3773-MER), ... 著者 Natchiar, S.K, Myasnikov, A.G, Kratzat, H, Hazemann, I, Klaholz, B.P. 登録日 2019-03-12 公開日 2019-04-24 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Visualization of chemical modifications in the human 80S ribosome structure. Nature, 551, 2017
6R55	Crystal structure of PPEP-1(E184K) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Pro-Pro endopeptidase, ZINC ION 著者 Pichlo, C, Baumann, U. 登録日 2019-03-24 公開日 2019-06-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.401 Å) 主引用文献 Molecular determinants of the mechanism and substrate specificity ofClostridium difficileproline-proline endopeptidase-1. J.Biol.Chem., 294, 2019
6R7S	Human Serum Albumin, complexed with Sulfasalazine 分子名称: 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID, DIMETHYL SULFOXIDE, SULFATE ION, ... 著者 Schreuder, H.A, Liesum, A. 登録日 2019-03-29 公開日 2020-04-08 最終更新日 2020-05-13 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Resolving Binding Events on the Multifunctional Human Serum Albumin. Chemmedchem, 15, 2020
6RFO	ERK2 MAP kinase with the activation loop of p38alpha 分子名称: Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 14,Mitogen-activated protein kinase 1 著者 Livnah, O, Eitan-Wexler, M. 登録日 2019-04-15 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop. J.Biol.Chem., 295, 2020
5IUJ	Crystal structure of the DesK-DesR complex in the phosphotransfer state with low Mg2+ (20 mM) 分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... 著者 Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A. 登録日 2016-03-18 公開日 2016-12-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action. Elife, 5, 2016
5IUL	Crystal structure of the DesK-DesR complex in the phosphotransfer state with high Mg2+ (150 mM) and BeF3 分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... 著者 Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A. 登録日 2016-03-18 公開日 2016-12-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.153 Å) 主引用文献 Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action. Elife, 5, 2016
5IUK	Crystal structure of the DesK-DesR complex in the phosphotransfer state with high Mg2+ (150 mM) 分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... 著者 Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A. 登録日 2016-03-18 公開日 2016-12-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action. Elife, 5, 2016
6QHN	Metagenome-derived salicylaldehyde dehydrogenase from alpine soil in complex with protocatechuic acid 分子名称: 3,4-DIHYDROXYBENZOIC ACID, GLYCEROL, SALICYLALDEHYDE DEHYDROGENASE 著者 Hakansson, M, Svensson, L.A, Shamsudeen, D.U, Allen, C.C.R. 登録日 2019-01-17 公開日 2020-02-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Expression, purification and crystallization of a novel metagenome-derived salicylaldehyde dehydrogenase from Alpine soil. Acta Crystallogr.,Sect.F, 78, 2022
2Q0F	Terminal uridylyl transferase 4 from Trypanosoma brucei with bound UTP and UMP 分子名称: MAGNESIUM ION, RNA uridylyl transferase, URIDINE 5'-TRIPHOSPHATE, ... 著者 Stagno, J, Luecke, H. 登録日 2007-05-21 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases. Proc.Natl.Acad.Sci.Usa, 104, 2007
3CSJ	Human glutathione s-transferase p1-1 in complex with chlorambucil 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORAMBUCIL, CHLORIDE ION, ... 著者 Parker, L.J. 登録日 2008-04-09 公開日 2008-07-01 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants. J.Mol.Biol., 380, 2008
3DD3	Crystal Structure of the Glutathione Transferase Pi enzyme in complex with the bifunctional inhibitor, Etharapta 分子名称: (eta6-benzene)ruthenium, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, ... 著者 Parker, L.J. 登録日 2008-06-05 公開日 2009-04-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Rational design of an organometallic glutathione transferase inhibitor Angew.Chem.Int.Ed.Engl., 48, 2009
2Q8M	T-like Fructose-1,6-bisphosphatase from Escherichia coli with AMP, Glucose 6-phosphate, and Fructose 1,6-bisphosphate bound 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 6-O-phosphono-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ... 著者 Hines, J.K, Kruesel, C.E, Fromm, H.J, Honzatko, R.B. 登録日 2007-06-11 公開日 2007-06-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure of Inhibited Fructose-1,6-bisphosphatase from Escherichia coli: DISTINCT ALLOSTERIC INHIBITION SITES FOR AMP AND GLUCOSE 6-PHOSPHATE AND THE CHARACTERIZATION OF A GLUCONEOGENIC SWITCH. J.Biol.Chem., 282, 2007
2PML	Crystal structure of PfPK7 in complex with an ATP analogue 分子名称: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ser/Thr protein kinase 著者 Merckx, A, Echalier, A, Noble, M, Endicott, J. 登録日 2007-04-23 公開日 2008-01-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of PfPK7 an atypical protein kinase from P. falciparum identify a novel activation motif and leads for inhibitor design To be Published
3CSI	Crystal Structure of the Glutathione Transferase Pi allelic variant*C, I104V/A113V, in complex with the Chlorambucil-Glutathione Conjugate 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CARBONATE ION, ... 著者 Parker, L.J. 登録日 2008-04-09 公開日 2008-07-01 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants. J.Mol.Biol., 380, 2008
2Q0C	Terminal uridylyl transferase 4 from Trypanosoma brucei with bound CTP 分子名称: CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA uridylyl transferase 著者 Stagno, J, Luecke, H. 登録日 2007-05-21 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases. Proc.Natl.Acad.Sci.Usa, 104, 2007
6AQK	Crystal structure of the C-terminal toxin domain of RHS2 from Yersinia entomophaga 分子名称: BROMIDE ION, CHLORIDE ION, PLATINUM (II) ION, ... 著者 Busby, J.N, Hurst, M.R.H, Lott, J.S. 登録日 2017-08-20 公開日 2018-08-22 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the C-terminal toxin domain of RHS2 from Yersinia entomophaga To be published
2Q0E	Terminal uridylyl transferase 4 from Trypanosoma brucei with bound GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA uridylyl transferase 著者 Stagno, J, Luecke, H. 登録日 2007-05-21 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases. Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q0D	Terminal uridylyl transferase 4 from Trypanosoma brucei with bound ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA uridylyl transferase 著者 Stagno, J, Luecke, H. 登録日 2007-05-21 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases. Proc.Natl.Acad.Sci.Usa, 104, 2007
3CSH	Crystal Structure of Glutathione Transferase Pi in complex with the Chlorambucil-Glutathione Conjugate 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... 著者 Parker, L.J. 登録日 2008-04-09 公開日 2008-07-01 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants. J.Mol.Biol., 380, 2008
6BCD	Crystal structure of Rev7-K44A/R124A/A135D in complex with Rev3-RBM2 (residues 1988-2014) 分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B 著者 Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M. 登録日 2017-10-20 公開日 2018-08-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6Y1E	Crystal structure of human glutathione transferase P1-1 (hGSTP1-1) that was co-crystallised in the presence of indanyloxyacetic acid-94 (IAA-94) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[[6,7-bis(chloranyl)-2-cyclopentyl-2-methyl-1-oxidanylidene-3~{H}-inden-5-yl]oxy]ethanoic acid, GLUTATHIONE, ... 著者 Pandian, R, Worth, R, Thangaraj, V, Sayed, Y, Dirr, H.W. 登録日 2020-02-12 公開日 2020-03-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.402 Å) 主引用文献 The interaction of IAA-94 with the soluble conformation of the CLIC1 protein and its structural homolog hGSTP1-1 To Be Published
6BDN	Crystal structure of human TAO3 kinase binding ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Aleshin, A.E, Bankton, L.A, Pinkerton, A, Courtneidge, S.A, Liddington, R.C. 登録日 2017-10-23 公開日 2019-04-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of human TAO3 kinase binding ADP To Be Published
6BLK	Mycobacterial sensor histidine kinase MprB 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Signal transduction histidine-protein kinase/phosphatase mprB 著者 Li, J, Korotkova, N, Korotkov, K.V. 登録日 2017-11-10 公開日 2017-11-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.552 Å) 主引用文献 Mycobacterial sensor histidine kinase MprB to be published
6BI7	Crystal structure of Rev7-WT/Rev3 as a monomer under high-salt conditions 分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B 著者 Rizzo, A.A, Korzhnev, D.M, Hao, B, Li, Y. 登録日 2017-11-01 公開日 2018-08-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BO1	Mono-adduct formed after 3 days in the reaction of dichlorido(1,3-dimethylbenzimidazol-2-ylidene)(eta6-p-cymene)ruthenium(II) with HEWL 分子名称: Lysozyme C, SODIUM ION, dichloro(1,3-dimethyl-1H-benzimidazol-3-ium-2-yl)ruthenium 著者 Sullivan, M.P, Hartinger, C.G, Goldstone, D.C. 登録日 2017-11-17 公開日 2018-05-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Unexpected arene ligand exchange results in the oxidation of an organoruthenium anticancer agent: the first X-ray structure of a protein-Ru(carbene) adduct. Chem. Commun. (Camb.), 54, 2018

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