High-resolution cryo-EM structure of the human 80S ribosome

This is a large structure.

Summary for 6QZP

EMDB information3883
Descriptor28S rRNA (3773-MER), 5S rRNA (120-MER), 5.8S rRNA (156-MER), ... (86 entities in total)
Functional Keywordshuman 80s ribosome, rrna, rrna modifications, high-resolution cryo-em, ribosome
Biological sourceHomo sapiens
Total number of polymer chains81
Total molecular weight3254785.8
Natchiar, S.K.,Myasnikov, A.G.,Kratzat, H.,Hazemann, I.,Klaholz, B.P. (deposition date: 2019-03-12, release date: 2019-04-24, Last modification date: 2019-05-29)
Primary citation
Natchiar, S.K.,Myasnikov, A.G.,Kratzat, H.,Hazemann, I.,Klaholz, B.P.
Visualization of chemical modifications in the human 80S ribosome structure.
Nature, 551:472-477, 2017
PubMed: 29143818 (PDB entries with the same primary citation)
DOI: 10.1038/nature24482
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone5 0.4% 3.7% 0.46MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload