5IUK

Crystal structure of the DesK-DesR complex in the phosphotransfer state with high Mg2+ (150 mM)

Summary for 5IUK

Entry DOI	10.2210/pdb5iuk/pdb
Related	5IUJ 5IUL 5IUM 5IUN
Descriptor	Sensor histidine kinase DesK, Transcriptional regulatory protein DesR, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (6 entities in total)
Functional Keywords	two-component regulatory system, kinase, response regulator, phosphotransfer complex, phosphotransfer, transferase, transferase-gene regulation complex, transferase/gene regulation
Biological source	Bacillus subtilis More
Cellular location	Cell membrane ; Multi-pass membrane protein : O34757 Cytoplasm : O34723
Total number of polymer chains	6
Total formula weight	132263.65
Authors	Trajtenberg, F.,Imelio, J.A.,Larrieux, N.,Buschiazzo, A. (deposition date: 2016-03-18, release date: 2016-12-21, Last modification date: 2024-03-06)
Primary citation	Trajtenberg, F.,Imelio, J.A.,Machado, M.R.,Larrieux, N.,Marti, M.A.,Obal, G.,Mechaly, A.E.,Buschiazzo, A. Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action. Elife, 5:-, 2016 Cited by PubMed: 27938660 DOI: 10.7554/eLife.21422 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation