2Q8M

T-like Fructose-1,6-bisphosphatase from Escherichia coli with AMP, Glucose 6-phosphate, and Fructose 1,6-bisphosphate bound

Summary for 2Q8M

Entry DOI	10.2210/pdb2q8m/pdb
Related	2GQ1 2OWZ 2OX3
Descriptor	Fructose-bisphosphatase, 6-O-phosphono-beta-D-glucopyranose, 1,6-di-O-phosphono-beta-D-fructofuranose, ... (7 entities in total)
Functional Keywords	glycolysis, gluconeogenesis, bacteria, carbohydrate metabolism, diabetes, protein-protein interactions, proteobacteria, gram-negative, protein crystallography, heterotrophic, allosteric regulation, hydrolase
Biological source	Shigella boydii
Total number of polymer chains	2
Total formula weight	76160.86
Authors	Hines, J.K.,Kruesel, C.E.,Fromm, H.J.,Honzatko, R.B. (deposition date: 2007-06-11, release date: 2007-06-19, Last modification date: 2023-11-15)
Primary citation	Hines, J.K.,Kruesel, C.E.,Fromm, H.J.,Honzatko, R.B. Structure of Inhibited Fructose-1,6-bisphosphatase from Escherichia coli: DISTINCT ALLOSTERIC INHIBITION SITES FOR AMP AND GLUCOSE 6-PHOSPHATE AND THE CHARACTERIZATION OF A GLUCONEOGENIC SWITCH. J.Biol.Chem., 282:24697-24706, 2007 Cited by PubMed: 17567577 DOI: 10.1074/jbc.M703580200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation