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6RFO

ERK2 MAP kinase with the activation loop of p38alpha

Summary for 6RFO
Entry DOI10.2210/pdb6rfo/pdb
Related1ERK
DescriptorMitogen-activated protein kinase 1,Mitogen-activated protein kinase 14,Mitogen-activated protein kinase 1 (2 entities in total)
Functional Keywordsnled, effectors, t3ss, map kinase, phosphorylation, transferase
Biological sourceRattus norvegicus (Norway Rat)
More
Total number of polymer chains1
Total formula weight42862.23
Authors
Livnah, O.,Eitan-Wexler, M. (deposition date: 2019-04-15, release date: 2020-05-27, Last modification date: 2024-01-24)
Primary citationGur-Arie, L.,Eitan-Wexler, M.,Weinberger, N.,Rosenshine, I.,Livnah, O.
The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop.
J.Biol.Chem., 295:9409-9420, 2020
Cited by
PubMed: 32404367
DOI: 10.1074/jbc.RA120.013590
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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