6RFO
ERK2 MAP kinase with the activation loop of p38alpha
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 14,Mitogen-activated protein kinase 1 | polymer | 372 | 42862.2 | 1 | UniProt (P63086) UniProt (Q16539) Pfam (PF00069) In PDB | Rattus norvegicus (Norway Rat) | MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAPK 2,MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a,MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAPK 2 |
2 | water | water | 18.0 | 173 | Chemie (HOH) |
Sequence modifications
A: -7 - 158 (UniProt: P63086)
A: 159 - 185 (UniProt: Q16539)
A: 186 - 358 (UniProt: P63086)
PDB | External Database | Details |
---|---|---|
Met -27 | - | initiating methionine |
Gly -26 | - | expression tag |
Ser -25 | - | expression tag |
Ser -24 | - | expression tag |
His -23 | - | expression tag |
His -22 | - | expression tag |
His -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
Gly -15 | - | expression tag |
Leu -14 | - | expression tag |
Val -13 | - | expression tag |
Pro -12 | - | expression tag |
Arg -11 | - | expression tag |
Gly -10 | - | expression tag |
Ser -9 | - | expression tag |
His -8 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Asp 160 | Glu 163 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42862.2 | |
All* | Total formula weight | 42862.2 |