PDB: 8861 件ウェブページステータス検索Chemie searchBIRD

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3QYZ	Crystal structure of ERK2 in complex with an inhibitor 分子名称: 5'-azido-8-bromo-5'-deoxyadenosine, BETA-MERCAPTOETHANOL, DIMETHYL SULFOXIDE, ... 著者 Gelin, M, Pochet, S, Hoh, F, Pirochi, M, Guichou, J.-F, Ferrer, J.-L, Labesse, G. 登録日 2011-03-04 公開日 2011-08-24 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 In-plate protein crystallization, in situ ligand soaking and X-ray diffraction. Acta Crystallogr.,Sect.D, 67, 2011
5HRL	The crystal structure of AsfvPolX: 1nt-gap(P) DNA2: dGTP ternary complex. 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*TP*CP*TP*AP*TP*GP*TP*GP*TP*AP*CP*TP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*AP*GP*TP*AP*CP*A)-3'), ... 著者 Chen, Y.Q, Zhang, J, Gan, J.H. 登録日 2016-01-23 公開日 2017-01-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1 To Be Published
3QYW	Crystal structure of ERK2 in complex with an inhibitor 分子名称: 6-(3-bromophenyl)-7H-purin-2-amine, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... 著者 Gelin, M, Pochet, S, Hoh, F, Pirochi, M, Guichou, J.-F, Ferrer, J.-L, Labesse, G. 登録日 2011-03-04 公開日 2011-08-24 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 In-plate protein crystallization, in situ ligand soaking and X-ray diffraction. Acta Crystallogr.,Sect.D, 67, 2011
8REV	Structure of XPD stalled at a Y-fork DNA containing a interstrand crosslink 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase CHL1, DNA (46-MER), ... 著者 Kuper, J, Hove, T, Kisker, C. 登録日 2023-12-12 公開日 2024-05-29 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 XPD stalled on cross-linked DNA provides insight into damage verification. Nat.Struct.Mol.Biol., 2024
5JVT	Crystal structure of the DNA binding domain of transcription factor FLI1 in complex with an 11-mer DNA GACCGGAAGTG 分子名称: DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), Friend leukemia integration 1 transcription factor, ... 著者 Hou, C, Tsodikov, O.V. 登録日 2016-05-11 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1. Nucleic Acids Res., 44, 2016
4R9W	Crystal structure of platelet factor 4 complexed with fondaparinux 分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, Platelet factor 4 著者 Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. 登録日 2014-09-08 公開日 2015-12-16 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Atomic description of the immune complex involved in heparin-induced thrombocytopenia. Nat Commun, 6, 2015
5QS6	PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z44592329 分子名称: N-phenyl-N'-pyridin-3-ylurea, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Fernandez-Cid, A, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-06-19 公開日 2019-08-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 PanDDA analysis group deposition To Be Published
4R9Y	Crystal structure of KKOFab in complex with platelet factor 4 分子名称: Platelet factor 4, Platelet factor 4 antibody KKO heavy chain, Platelet factor 4 antibody KKO light chain 著者 Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. 登録日 2014-09-08 公開日 2015-12-16 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (4.11 Å) 主引用文献 Atomic description of the immune complex involved in heparin-induced thrombocytopenia. Nat Commun, 6, 2015
4DTX	RB69 DNA Polymerase Ternary Complex with dTTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair 分子名称: CALCIUM ION, DNA polymerase, DNA primer, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTM	RB69 DNA Polymerase Ternary Complex with dCTP Opposite an Abasic Site and ddG/dC as the Penultimate Base-pair 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTP	RB69 DNA Polymerase Ternary Complex with dGTP Opposite an Abasic Site and ddA/dT as the Penultimate Base-pair 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTO	RB69 DNA Polymerase Ternary Complex with dCTP Opposite an Abasic Site and ddA/dT as the Penultimate Base-pair 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTR	RB69 DNA Polymerase Ternary Complex with dATP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTS	RB69 DNA Polymerase Ternary Complex with dCTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTU	RB69 DNA Polymerase Ternary Complex with dGTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
5V8W	Crystal structure of human Integrator IntS9-IntS11 CTD complex 分子名称: Integrator complex subunit 11, Integrator complex subunit 9 著者 Wu, Y, Tong, L. 登録日 2017-03-22 公開日 2017-04-12 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular basis for the interaction between Integrator subunits IntS9 and IntS11 and its functional importance. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8G94	Structure of CD69-bound S1PR1 coupled to heterotrimeric Gi 分子名称: Early activation antigen CD69, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Chen, H, Li, X. 登録日 2023-02-21 公開日 2023-04-19 最終更新日 2023-04-26 実験手法 ELECTRON MICROSCOPY (3.15 Å) 主引用文献 Transmembrane protein CD69 acts as an S1PR1 agonist. Elife, 12, 2023
4DTN	RB69 DNA Polymerase Ternary Complex with dATP Opposite an Abasic Site and ddA/dT as the Penultimate Base-pair 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
6W4S	Structure of apo human ferroportin in lipid nanodisc 分子名称: Fab45D8 Heavy Chain, Fab45D8 Light Chain, Solute carrier family 40 member 1 著者 Billesboelle, C.B, Azumaya, C.M, Gonen, S, Powers, A, Kretsch, R.C, Schneider, S, Arvedson, T, Dror, R.O, Cheng, Y, Manglik, A. 登録日 2020-03-11 公開日 2020-09-09 最終更新日 2020-11-11 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms. Nature, 586, 2020
7L1G	PRMT5-MEP50 Complexed with SAM 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Methylosome protein 50, ... 著者 Palte, R.L. 登録日 2020-12-14 公開日 2021-04-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Development of a Flexible and Robust Synthesis of Tetrahydrofuro[3,4- b ]furan Nucleoside Analogues. J.Org.Chem., 86, 2021
3QB1	Interleukin-2 mutant D10 分子名称: Interleukin-2 著者 Levin, A.M, Bates, D.L, Ring, A.M, Lin, J.T, Su, L, Krieg, C, Bowman, G.R, Novick, P, Pande, V.S, Khort, H.E, Boyman, O, Fathman, C.G, Garcia, K.C. 登録日 2011-01-12 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Exploiting a natural conformational switch to engineer an interleukin-2 'superkine' Nature, 484, 2012
1A2B	HUMAN RHOA COMPLEXED WITH GTP ANALOGUE 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA 著者 Ihara, K, Muraguchi, S, Kato, M, Shimizu, T, Shirakawa, M, Kuroda, S, Kaibuchi, K, Hakoshima, T. 登録日 1997-12-26 公開日 1998-06-17 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue. J.Biol.Chem., 273, 1998
2H24	Crystal structure of human IL-10 分子名称: Interleukin-10 著者 Yoon, S.I, Walter, M.R. 登録日 2006-05-18 公開日 2006-10-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex. J.Biol.Chem., 281, 2006
2YOL	West Nile Virus NS2B-NS3 protease in complex with 3,4- dichlorophenylacetyl-Lys-Lys-GCMA 分子名称: (S)-6-amino-N-((S)-6-amino-1-(((1r,4S)-4-guanidinocyclohexyl)methylamino)-1-oxohexan-2-yl)-2-(2-(3,4-dichlorophenyl)acetamido)hexanamide, CHLORIDE ION, NICKEL (II) ION, ... 著者 Hammamy, M.Z, Haase, C, Hammami, M, Hilgenfeld, R, Steinmetzer, T. 登録日 2012-10-25 公開日 2013-03-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Development and Characterization of New Peptidomimetic Inhibitors of the West Nile Virus Ns2B-Ns3 Protease. Chemmedchem, 8, 2013
3P4F	Structural and biochemical insights into MLL1 core complex assembly and regulation. 分子名称: Histone-lysine N-methyltransferase MLL, Retinoblastoma-binding protein 5, WD repeat-containing protein 5 著者 Avdic, V, Zhang, P, Lanouette, S, Groulx, A, Tremblay, V, Brunzelle, J.B, Couture, J.-F. 登録日 2010-10-06 公開日 2010-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural and biochemical insights into MLL1 core complex assembly. Structure, 19, 2011

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