3QYZ

Crystal structure of ERK2 in complex with an inhibitor

Summary for 3QYZ

Entry DOI	10.2210/pdb3qyz/pdb
Related	3QYU 3QYW
Descriptor	Mitogen-activated protein kinase 1, 5'-azido-8-bromo-5'-deoxyadenosine, DIMETHYL SULFOXIDE, ... (6 entities in total)
Functional Keywords	transferase, serine/threonine-protein kinase, atp-binding cell cycle, phosphorylation, protein kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Rattus norvegicus (brown rat,rat,rats)
Cellular location	Cytoplasm, cytoskeleton, spindle : P63086
Total number of polymer chains	1
Total formula weight	43736.42
Authors	Gelin, M.,Pochet, S.,Hoh, F.,Pirochi, M.,Guichou, J.-F.,Ferrer, J.-L.,Labesse, G. (deposition date: 2011-03-04, release date: 2011-08-24, Last modification date: 2017-11-08)
Primary citation	le Maire, A.,Gelin, M.,Pochet, S.,Hoh, F.,Pirocchi, M.,Guichou, J.F.,Ferrer, J.L.,Labesse, G. In-plate protein crystallization, in situ ligand soaking and X-ray diffraction. Acta Crystallogr.,Sect.D, 67:747-755, 2011 Cited by PubMed: 21904027 DOI: 10.1107/S0907444911023249 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.46 Å)

Structure validation