3QYZ
Crystal structure of ERK2 in complex with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 1 | polymer | 364 | 42235.5 | 1 | UniProt (P63086) Pfam (PF00069) | Rattus norvegicus (brown rat rat rats) | MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2 |
| 2 | B (A) | 5'-azido-8-bromo-5'-deoxyadenosine | non-polymer | 371.1 | 1 | Chemie (Z8B) | |||
| 3 | C, D, E, F, G... (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 11 | Chemie (DMS) | |||
| 4 | N, O (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | P (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 6 | Q (A) | water | water | 18.0 | 448 | Chemie (HOH) |
Sequence modifications
A: 1 - 358 (UniProt: P63086)
| PDB | External Database | Details |
|---|---|---|
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42235.5 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1500.9 | |
| All* | Total formula weight | 43736.4 |
