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3P4F

Structural and biochemical insights into MLL1 core complex assembly and regulation.

Summary for 3P4F
Entry DOI10.2210/pdb3p4f/pdb
Related2H14
DescriptorWD repeat-containing protein 5, Retinoblastoma-binding protein 5, Histone-lysine N-methyltransferase MLL, ... (4 entities in total)
Functional Keywordsbeta-propeller, scaffold, mll1, rbbp5, transcription
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus : P61964 Q15291
Nucleus . MLL cleavage product N320: Nucleus. MLL cleavage product C180: Nucleus: Q03164
Total number of polymer chains3
Total formula weight37054.84
Authors
Avdic, V.,Zhang, P.,Lanouette, S.,Groulx, A.,Tremblay, V.,Brunzelle, J.B.,Couture, J.-F. (deposition date: 2010-10-06, release date: 2010-12-08, Last modification date: 2023-09-06)
Primary citationAvdic, V.,Zhang, P.,Lanouette, S.,Groulx, A.,Tremblay, V.,Brunzelle, J.,Couture, J.-F.
Structural and biochemical insights into MLL1 core complex assembly.
Structure, 19:101-108, 2011
Cited by
PubMed: 21220120
DOI: 10.1016/j.str.2010.09.022
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.35 Å)
Structure validation

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