3P4F
Structural and biochemical insights into MLL1 core complex assembly and regulation.
Summary for 3P4F
Entry DOI | 10.2210/pdb3p4f/pdb |
Related | 2H14 |
Descriptor | WD repeat-containing protein 5, Retinoblastoma-binding protein 5, Histone-lysine N-methyltransferase MLL, ... (4 entities in total) |
Functional Keywords | beta-propeller, scaffold, mll1, rbbp5, transcription |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : P61964 Q15291 Nucleus . MLL cleavage product N320: Nucleus. MLL cleavage product C180: Nucleus: Q03164 |
Total number of polymer chains | 3 |
Total formula weight | 37054.84 |
Authors | Avdic, V.,Zhang, P.,Lanouette, S.,Groulx, A.,Tremblay, V.,Brunzelle, J.B.,Couture, J.-F. (deposition date: 2010-10-06, release date: 2010-12-08, Last modification date: 2023-09-06) |
Primary citation | Avdic, V.,Zhang, P.,Lanouette, S.,Groulx, A.,Tremblay, V.,Brunzelle, J.,Couture, J.-F. Structural and biochemical insights into MLL1 core complex assembly. Structure, 19:101-108, 2011 Cited by PubMed: 21220120DOI: 10.1016/j.str.2010.09.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
Download full validation report